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Merck
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Key Documents

L5900

Sigma-Aldrich

Linoleic Acid-Water Soluble

powder, BioReagent, suitable for cell culture

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About This Item

Code UNSPSC :
12352211
Nomenclature NACRES :
NA.75

Source biologique

plant (Safflower oil)

Niveau de qualité

200

Gamme de produits

BioReagent

Forme

powder

Technique(s)

cell culture | mammalian: suitable

Solubilité

H2O: 50 mg/mL

Température de stockage

−20°C

Application

Linoleic acid-water soluble has been used as a component of fatting media for the in vitro steatosis induction of primary human hepatocytes (PHH).

Actions biochimiques/physiologiques

Linoleic acid (LA) is an arachidonic acid precursor, which is present in vegetable oils. It enhances wound healing in diabetic rats. LA triggers tumor and apoptosis in colorectal cancer cells. The levels of LA in adipose tissue and platelets are associated with coronary artery disease. Linoleic acid binds to molecules, such as bovine serum albumin (BSA) or cyclodextrin for use in cell culture.

Autres remarques

Contains approx. 30 mg of linoleic acid per gram; balance methyl-β-cyclodextrin.
Package size based on linoleic acid content.

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H319

Conseils de prudence

P305 + P351 + P338

Classification des risques

Eye Irrit. 2

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Chemical-defined and albumin-free generation of human atrial and ventricular myocytes from human pluripotent stem cells
Pei F, et al.
Stem Cell Research, 19, 94-103 (2017)
Enhancement effects of BSA and linoleic acid on hybridoma cell growth and antibody production
Cell Culture Engineering IV, 51-56 (1994)
María Alejandra Moreno et al.
Journal of ethnopharmacology, 216, 283-294 (2018-01-09)
The Argentinean medicinal plant Tetraglochin andina Ciald, formerly classified as T. cristatum (Britton) Rothm is used in traditional medicine by inhabitants from Argentinean northwestern highlands (Puna) to treat candidiasis and as anti-inflammatory. To assess the potential of the crude drug
Takashi Okumura et al.
Oncotarget, 8(11), 18280-18295 (2017-04-15)
Pancreatic cancer progression involves components of the tumor microenvironment, including stellate cells, immune cells, endothelial cells, and the extracellular matrix. Although peripancreatic fat is the main stromal component involved in extra-pancreatic invasion, its roles in local invasion and metastasis of
B R Abdel-Halim
Theriogenology, 114, 143-148 (2018-04-07)
The current study was conducted to investigate the effect of linoleic acid-treated oocytes during in vitro maturation (IVM) on cumulus cell expansion, oocyte nuclear maturation, blastocyst development and DNA damage of cumulus cells and how its effects were alleviated by supplementation
Afficher tous les articles scientifiques apparentés

Articles

Linoleic acid in Cell Culture

Importance and uses of linoleic acid in serum-free eukaryotic, including hybridoma and Chinese Hamster Ovary (CHO) cell, cultures

Oleic Acid in Cell Culture

How the unsaturated fatty acid, oleic acid and other cell culture components affect the performance of serum-free, protein-free cell culture systems used for biomanufacturing heterologous proteins including monoclonal antibodies.

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