L5288

Latrunculin B

from Latruncula magnifica, ≥80% (HPLC), solid, actin polymerization inhibitor

• Synonyme(s) : LAT-B
• Formule empirique (notation de Hill): C₂₀H₂₉NSO₅
• Numéro CAS: 76343-94-7
• Poids moléculaire : 395.51
• Numéro MDL: MFCD00270879
• Code UNSPSC : 12352200
• ID de substance PubChem : 329817621
• Nomenclature NACRES : NA.77

Propriétés

• product name: Latrunculin B from Latruncula magnifica, ≥80% (HPLC), solid
• Niveau de qualité: 200
• Pureté: ≥80% (HPLC)
• Forme: solid
• Poids mol.: 395.5
• Solubilité: ethanol: soluble
• Température de stockage: −20°C
• Chaîne SMILES: C[C@H]1CC[C@@H]2C[C@H](C[C@@](O)(O2)[C@@H]3CSC(=O)N3)OC(=O)C=C(C)CCC=C1
• InChI: 1S/C20H29NO5S/c1-13-5-3-4-6-14(2)9-18(22)25-16-10-15(8-7-13)26-20(24,11-16)17-12-27-19(23)21-17/h3,5,9,13,15-17,24H,4,6-8,10-12H2,1-2H3,(H,21,23)/b5-3-,14-9-/t13-,15-,16-,17+,20-/m1/s1
• Clé InChI: NSHPHXHGRHSMIK-JRIKCGFMSA-N

Description

Description générale

Latrunculin B is a macrocyclic toxin, which is produced by Latruncula magnifica.

Application

Latrunculin B from Latruncula magnifica has been used for actin depolymerisation in various experiments. It has also been used as a component in bone marrow-derived dendritic cell (BMDC) complete medium, to study the formation of tubules from phagosomes in dendritic cells.

Actions biochimiques/physiologiques

Latrunculin B inhibits actin polymerization in vitro. Latrunculin B disrupts microfilament-mediated processes.

Autres remarques

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)