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L2752

Sigma-Aldrich

Leu-Leu

>98% (TLC), suitable for ligand binding assays

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About This Item

Formule empirique (notation de Hill):
C12H24N2O3
Numéro CAS:
3303-31-9
Poids moléculaire :
244.33
Numéro CE :
221-976-6
Numéro MDL:
MFCD00065185
Code UNSPSC :
12352202
ID de substance PubChem :
24896323
Nomenclature NACRES :
NA.26

product name

Leu-Leu,

Pureté

>98% (TLC)

Niveau de qualité

200

Forme

powder

Technique(s)

ligand binding assay: suitable

Couleur

white to off-white

Température de stockage

−20°C

Chaîne SMILES 

CC(C)C[C@H](N)C(=O)N[C@@H](CC(C)C)C(O)=O

InChI

1S/C12H24N2O3/c1-7(2)5-9(13)11(15)14-10(12(16)17)6-8(3)4/h7-10H,5-6,13H2,1-4H3,(H,14,15)(H,16,17)/t9-,10-/m0/s1

Clé InChI

LCPYQJIKPJDLLB-UWVGGRQHSA-N

Catégories apparentées

Amino Acid Sequence

Leu-Leu

Actions biochimiques/physiologiques

Leucylleucine (Leu-Leu) may be used to study the functionality of dileucine motifs such as the motif responsible for internalization and targeting of vesicular acetylcholine transporter and clathrin adaptors AP-1 and AP-2.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

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Guoqing Wang et al.
Cellular and molecular neurobiology, 41(1), 163-171 (2020-04-23)
Traditionally, hydrogen peroxide (H2O2) was formed from cellular oxidative metabolism and often viewed as toxic waste. In fact, H2O2 was a benefit messenger for neuron-glia signaling and synaptic transmission. Thus, H2O2 was a double-edged sword and neuroprotection vs. neurotoxicity produced
Lingling Zhang et al.
Oncogene, 39(49), 7196-7208 (2020-10-11)
Metastasis is responsible for the death of most breast cancer patients. Robo1 has been implicated as a tumor suppressor for various cancers including breast cancer. However, it is not well understood how Robo1 expression is regulated during tumorigenesis. In this
Yanzhen Zhou et al.
Journal of neuroinflammation, 15(1), 161-161 (2018-05-29)
Microglia-mediated neuroinflammation is recognized to mainly contribute to the pathogenesis of Parkinson's disease (PD). Tetrahydroxystilbene glucoside (TSG) has been proved to be beneficial for health with a great number of pharmacological properties. We examined the effects of TSG against dopamine
A van Boven et al.
Biochimie, 70(4), 535-542 (1988-04-01)
Different strains of Lactococcus lactis ssp. cremoris hydrolyze peptides at different rates while the cell-free extracts of these strains all show the same or much higher rates of hydrolysis. These observations indicate that the uptake of peptides is the rate-limiting
S Martinez-Arca et al.
Journal of cell science, 113 ( Pt 10), 1705-1715 (2000-04-19)
The mechanisms by which the insulin-sensitive glucose transporter, GLUT4, is targeted and retained in a storage compartment near to the Golgi complex are poorly understood. Here we report that removal of the carboxyl-terminal acidic Pro(505)AspGluAsnAsp(509) sequence prevents the storage of
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