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I9148

Sigma-Aldrich

Sodium iodoacetate

powder, ≥98%

Synonyme(s) :

Iodoacetic acid sodium salt

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About This Item

Formule linéaire :
ICH2COONa
Numéro CAS:
305-53-3
Poids moléculaire :
207.93
Numéro Beilstein :
4009322
Numéro CE :
206-165-7
Numéro MDL:
MFCD00002686
Code UNSPSC :
12352202
ID de substance PubChem :
24896151
Nomenclature NACRES :
NA.77

product name

Sodium iodoacetate, ≥98%, BioUltra

Source biologique

synthetic (organic)

Niveau de qualité

200

Gamme de produits

BioUltra

Pureté

≥98%

Forme

powder

Impuretés

≤0.0005% Phosphorus (P)
≤0.1% Insoluble matter

Pf

208 °C (dec.) (lit.)

Solubilité

H2O: 0.5 M, clear, colorless

Traces d'anions

sulfate (SO42-): ≤0.05%

Traces de cations

Al: ≤0.0005%
Ca: ≤0.001%
Cu: ≤0.001%
Fe: ≤0.0005%
K: ≤0.02%
Mg: ≤0.0005%
NH4+: ≤0.05%
Pb: ≤0.001%
Zn: ≤0.0005%

Température de stockage

−20°C

Chaîne SMILES 

[Na+].[O-]C(=O)CI

InChI

1S/C2H3IO2.Na/c3-1-2(4)5;/h1H2,(H,4,5);/q;+1/p-1

Clé InChI

AGDSCTQQXMDDCV-UHFFFAOYSA-M

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Application

Reagent for the modification of cysteine residues in proteins. Used in protein sequencing (including by Sanger in sequencing bovine insulin) to prevent oxidation of -SH sidechains.
Reagent for the modification of cysteine residues in proteins. Used to induce animal osteoarthritis model system, which mimics both symptoms and histopathology of the human disease.

Pictogrammes

Skull and crossbonesCorrosion
GHS06,GHS05

Mention d'avertissement

Danger

Mentions de danger

H301,H314

Classification des risques

Acute Tox. 3 Oral - Eye Dam. 1 - Skin Corr. 1B

Code de la classe de stockage

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

406.4 °F

Point d'éclair (°C)

208 °C

Équipement de protection individuelle

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Certificats d'analyse (COA)

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Helena Akerud et al.
American journal of physiology. Endocrinology and metabolism, 297(6), E1414-E1419 (2009-10-15)
It is generally believed that a relationship exists between muscle fatigue and intracellular accumulation of lactate. This reasoning is relevant to obstetrical issues. Myocytes in uterus work together during labor, and the contractions need to be strong and synchronized for
Mohammed Gagaoua et al.
Journal of agricultural and food chemistry, 63(30), 6799-6809 (2015-07-15)
Many studies on color biochemistry and protein biomarkers were undertaken in post-mortem beef muscles after ≥24 hours. The present study was conducted on Longissimus thoracis muscles of 21 Blond d'Aquitaine young bulls to evaluate the relationships between protein biomarkers present
Joon Shik Yoon et al.
American journal of physical medicine & rehabilitation, 94(8), 644-648 (2014-11-22)
The aim of this study was to investigate the potential of using phase-contrast radiography to detect early changes in articular cartilage in a mouse model of osteoarthritis. An iodoacetate-induced mouse model of osteoarthritis was used. Mice with iodoacetate-induced osteoarthritis were
K Nakyinsige et al.
Meat science, 98(4), 701-708 (2014-08-05)
This study assessed the effect of gas stunning which has not been conducted until now in comparison with slaughter without stunning on the welfare and meat quality of rabbits. Eighty male New Zealand White rabbits were divided into two groups
Hyunji Lee et al.
Bioscience, biotechnology, and biochemistry, 78(10), 1703-1709 (2014-10-03)
Deer bone extract has the potential to relieve the discomfort or the articular cartilaginous damage associated with osteoarthritic (OA) and may be useful as a natural supplement for OA treatment without serious side effects. We analyzed the expression of pro-inflammatory
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