G9910

Sodium glycodeoxycholate

BioXtra, ≥97% (HPLC)

• Synonyme(s) : 3α,12α-Dihydroxy-5β-cholan-24-oic acid N-(carboxymethyl)amide, Glycodeoxycholic acid sodium salt, Glycodesoxycholic acid, N-(3α,12α-Dihydroxy-24-oxocholan-24-yl)glycine
• Formule empirique (notation de Hill): C₂₆H₄₂NNaO₅
• Numéro CAS: 16409-34-0
• Poids moléculaire : 471.61
• Numéro CE : 240-455-4
• Numéro MDL: MFCD00036742
• Code UNSPSC : 12161900
• ID de substance PubChem : 24895386
• Nomenclature NACRES : NA.25

Propriétés

• Description: anionic
• Niveau de qualité: 200
• Gamme de produits: BioXtra
• Pureté: ≥97% (HPLC)
• Poids mol.: 471.61 g/mol
• Impuretés: ≤0.0025% Phosphorus (P); ≤0.1% Insoluble matter
• CMC: 2.1 mM
• Solubilité: H₂O: 0.1 M, clear to slightly hazy, colorless to almost colorless
• Traces d'anions: chloride (Cl^-): ≤1%; sulfate (SO₄^2-): ≤0.05%
• Traces de cations: Al: ≤0.0005%; Ca: ≤0.011%; Cu: ≤0.0005%; Fe: ≤0.001%; K: ≤0.005%; NH₄⁺: ≤0.05%; Pb: ≤0.001%; Zn: ≤0.003%
• Chaîne SMILES: [Na].[H][C@]12CC[C@@]3([H])[C@]4([H])CC[C@]([H])([C@H](C)CCC(=O)NCC(O)=O)[C@@]4(C)[C@@H](O)C[C@]3([H])[C@@]1(C)CC[C@@H](O)C2
• InChI: 1S/C26H43NO5.Na.H/c1-15(4-9-23(30)27-14-24(31)32)19-7-8-20-18-6-5-16-12-17(28)10-11-25(16,2)21(18)13-22(29)26(19,20)3;;/h15-22,28-29H,4-14H2,1-3H3,(H,27,30)(H,31,32);;/t15-,16-,17-,18+,19-,20+,21+,22+,25+,26-;;/m1../s1
• Clé InChI: BMYWWGPEKRLDGW-ZXMGEDLUSA-N

Description

Description générale

Sodium glycodeoxycholate is a bile salt that can be used to form biomimicking environments.

Application

Sodium glycodeoxycholate has been used in a study to develop more similar mimetic intestinal fluids to physiological fluids than those developed by mixed bile salt systems (MBS). It has also been used in a study to investigate Ca²⁺ buffering capability of bile salt micelles.

Actions biochimiques/physiologiques

Induces apoptosis in hepatocytes; may induce DNA cleavage.

Autres remarques

Bile Salt

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves