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Merck
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Key Documents

C5735

SAFC

L-Cystine

Fabrication pharma

Synonyme(s) :

(R,R)-3,3′-Dithiobis(acide 2-aminopropionique)

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About This Item

Formule linéaire :
[-SCH2CH(NH2)CO2H]2
Numéro CAS:
Poids moléculaire :
240.30
Numéro Beilstein :
1728094
Numéro CE :
Numéro MDL:
Code UNSPSC :
12352209
Nomenclature NACRES :
NA.26

Source biologique

non-animal source

Niveau de qualité

Pureté

≥98.5%

Forme

powder

Technique(s)

cell culture | mammalian: suitable

Impuretés

endotoxin, tested

Pf

>240 °C (dec.) (lit.)

Solubilité

1 M HCl: 100 mg/mL

Adéquation

suitable for manufacturing use

Application(s)

pharmaceutical (small molecule)

Chaîne SMILES 

N[C@@H](CSSC[C@H](N)C(O)=O)C(O)=O

InChI

1S/C6H12N2O4S2/c7-3(5(9)10)1-13-14-2-4(8)6(11)12/h3-4H,1-2,7-8H2,(H,9,10)(H,11,12)/t3-,4-/m0/s1

Clé InChI

LEVWYRKDKASIDU-IMJSIDKUSA-N

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Description générale

Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.

Informations légales

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Les clients ont également consulté

Philip J Hogg
Nature reviews. Cancer, 13(6), 425-431 (2013-05-11)
Protein action in nature is generally controlled by the amount of protein produced and by chemical modification of the protein, and both are often perturbed in cancer. The amino acid side chains and the peptide and disulphide bonds that bind
Serge-George Rosolen et al.
Advances in experimental medicine and biology, 775, 145-154 (2013-02-09)
In the 70s, the amino acid taurine was found essential for photoreceptor survival. Recently, we found that taurine depletion can also trigger retinal ganglion cell degeneration both in vitro and in vivo. Therefore, evaluation of taurine levels could be a
Martijn J Wilmer et al.
American journal of physiology. Renal physiology, 299(5), F905-F916 (2010-09-10)
Renal proximal tubules are highly sensitive to ischemic and toxic insults and are affected in diverse genetic disorders, of which nephropathic cystinosis is the most common. The disease is caused by mutations in the CTNS gene, encoding the lysosomal cystine
Anne C Conibear et al.
The Journal of biological chemistry, 288(15), 10830-10840 (2013-02-23)
θ-Defensins are ribosomally synthesized cyclic peptides found in the leukocytes of some primate species and have promising applications as antimicrobial agents and scaffolds for peptide drugs. The cyclic cystine ladder motif, comprising a cyclic peptide backbone and three parallel disulfide
Maisie Lo et al.
Journal of cellular physiology, 215(3), 593-602 (2008-01-09)
The x(c) (-) cystine/glutamate antiporter is a major plasma membrane transporter for the cellular uptake of cystine in exchange for intracellular glutamate. Its main functions in the body are mediation of cellular cystine uptake for synthesis of glutathione essential for

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