C4680

α-Cyclodextrin

powder, BioReagent, suitable for cell culture, ≥98%

• Synonyme(s) : α-Schardinger dextrin, Cyclohexaamylose, Cyclomaltohexaose
• Formule empirique (notation de Hill): C₃₆H₆₀O₃₀
• Numéro CAS: 10016-20-3
• Poids moléculaire : 972.84
• Numéro Beilstein : 79627
• Numéro CE : 233-007-4
• Numéro MDL: MFCD00078207
• Code UNSPSC : 12352201
• ID de substance PubChem : 24892712
• Nomenclature NACRES : NA.77

Propriétés

• Stérilité: non-sterile
• Niveau de qualité: 200
• Gamme de produits: BioReagent
• Pureté: ≥98%
• Forme: powder
• Technique(s): cell culture | mammalian: suitable
• Pf: >278 °C (dec.) (lit.)
• Solubilité: H₂O: 10 mg/mL
• Conditions d'expédition: ambient
• Température de stockage: room temp
• Chaîne SMILES: OC[C@H]1O[C@@H]2O[C@H]3[C@H](O)[C@@H](O)[C@H](O[C@@H]3CO)O[C@H]4[C@H](O)[C@@H](O)[C@H](O[C@@H]4CO)O[C@H]5[C@H](O)[C@@H](O)[C@H](O[C@@H]5CO)O[C@H]6[C@H](O)[C@@H](O)[C@H](O[C@@H]6CO)O[C@H]7[C@H](O)[C@@H](O)[C@H](O[C@@H]7CO)O[C@H]1[C@H](O)[C@H]2O
• InChI: 1S/C36H60O30/c37-1-7-25-13(43)19(49)31(55-7)62-26-8(2-38)57-33(21(51)15(26)45)64-28-10(4-40)59-35(23(53)17(28)47)66-30-12(6-42)60-36(24(54)18(30)48)65-29-11(5-41)58-34(22(52)16(29)46)63-27-9(3-39)56-32(61-25)20(50)14(27)44/h7-54H,1-6H2/t7-,8-,9-,10-,11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-/m1/s1
• Clé InChI: HFHDHCJBZVLPGP-RWMJIURBSA-N

Description

Description générale

α-Cyclodextrin (α-CD) is a cyclic oligosaccharide that consists of six glucopyranose units linked by α-(1,4) bonds. α-CD acts as a soluble dietary fiber and hence it is preferred to be widely used in food industry.

Application

Useful for the solubilization of nonpolar macromolecules such as fatty acids, lipids, and cholesterol for use in cell culture applications. α-Cyclodextrin has been used to solubilize odanacatib, a cathepsin K inhibitor.

Actions biochimiques/physiologiques

α-Cyclodextrin is found to form a firm complex with dietary fats. This way it decreases the bioavailability and absorption of fats. It is known to regulate triglyceride and leptin levels in serum. In rat models, α-Cyclodextrin is shown to induce insulin sensitivity and fecal fat excretion. Thus, α-cyclodextrin is considered to be effective for treating obesity and metabolic syndromes.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)