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56297

Sigma-Aldrich

Pinosylvin

≥97.0% (HPLC)

Synonyme(s) :

(E)-3,5-Stilbenediol, (E)-5-(2-Phenylethenyl)-1,3-benzenediol, 5-Styrylresorcinol, trans-3,5-Dihydroxystilbene, Pinosylvine

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About This Item

Formule empirique (notation de Hill):
C14H12O2
Numéro CAS:
22139-77-1
Poids moléculaire :
212.24
Numéro Beilstein :
1870942
Numéro MDL:
MFCD00210544
Code UNSPSC :
41116107
ID de substance PubChem :
329758200
Nomenclature NACRES :
NA.25

Niveau de qualité

100

Pureté

≥97.0% (HPLC)

Forme

solid

Conditions de stockage

protect from light

Pf

153-157 °C

Conditions d'expédition

wet ice

Température de stockage

2-8°C

Chaîne SMILES 

Oc1cc(O)cc(\C=C\c2ccccc2)c1

InChI

1S/C14H12O2/c15-13-8-12(9-14(16)10-13)7-6-11-4-2-1-3-5-11/h1-10,15-16H/b7-6+

Clé InChI

YCVPRTHEGLPYPB-VOTSOKGWSA-N

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Application

Pinosylvin, a pre-infectious stilbenoid toxin, is used to study its properties as a fungitoxin and therapeutic agent. Pinosylvin is used as a representative stilbene to study its biological actions and therapeutic value in processes such as cell survival, apoptosis and cell mobility.

Conditionnement

Bottomless glass bottle. Contents are inside inserted fused cone.

Attention

sensitive to oxidation

Pictogrammes

Exclamation markEnvironment
GHS07,GHS09

Mention d'avertissement

Warning

Mentions de danger

H315,H319,H335,H400

Classification des risques

Aquatic Acute 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organes cibles

Respiratory system

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Takao Koeduka et al.
Journal of bioscience and bioengineering, 127(5), 539-543 (2018-11-26)
Resveratrol and its methyl ethers, which belong to a class of natural polyphenol stilbenes, play important roles as biologically active compounds in plant defense as well as in human health. Although the biosynthetic pathway of resveratrol has been fully elucidated
Eunsil Jeong et al.
Phytotherapy research : PTR, 27(4), 610-617 (2012-06-28)
Pinosylvin is a phenolic compound mainly found in the Pinus species. To determine the vascular functions of pinosylvin, we first examined both proliferation and apoptosis of bovine aortic endothelial cells (BAECs) in the presence of pinosylvin. When BAECs were treated
Andrea Ganthaler et al.
Plant molecular biology, 94(3), 229-251 (2017-02-13)
Accumulation of phenolic needle metabolites in Norway spruce is regulated by many genes with small and additive effects and is correlated with the susceptibility against fungal attack. Norway spruce accumulates high foliar concentrations of secondary phenolic metabolites, with important functions
Eun-Jung Park et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 55, 424-433 (2013-01-22)
Pinosylvin, a naturally occurring trans-stilbenoid mainly found in Pinus species, has exhibited a potential cancer chemopreventive activity. However, the growth inhibitory activity against cancer cells and the underlying molecular mechanisms remain to be elucidated. Therefore, the anti-proliferative activity of pinosylvin
Mirka Laavola et al.
Molecules (Basel, Switzerland), 24(1) (2019-01-02)
Interleukin-6 (IL-6) is involved in the pathogenesis of various inflammatory diseases, like rheumatoid arthritis (RA). In the present study, we investigated the role of IL-6 in osteoarthritis (OA) patients and the effects of the stilbenoids monomethyl pinosylvin and pinosylvin on
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