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15721

Sigma-Aldrich

Polydatin

≥95% (HPLC)

Synonyme(s) :

Piceid, Reservatrol-3-β-mono-D-glucoside, Resveratrol 3-O-β-D-glucopyranoside

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About This Item

Formule empirique (notation de Hill):
C20H22O8
Numéro CAS:
65914-17-2
Poids moléculaire :
390.38
Numéro Beilstein :
54837
Code UNSPSC :
12352201
ID de substance PubChem :
329750984
Nomenclature NACRES :
NA.25

Niveau de qualité

100

Pureté

≥95% (HPLC)

Forme

powder

Activité optique

[α]1/D -66.0±2.0° in ethanol

Composition

carbon, 60.5-62.5%

Température de stockage

2-8°C

Chaîne SMILES 

OCC1O[C@@H](Oc2cc(O)cc(\C=C\c3ccc(O)cc3)c2)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C20H22O8/c21-10-16-17(24)18(25)19(26)20(28-16)27-15-8-12(7-14(23)9-15)2-1-11-3-5-13(22)6-4-11/h1-9,16-26H,10H2/b2-1+/t16?,17-,18+,19-,20-/m1/s1

Clé InChI

HSTZMXCBWJGKHG-AEGFYQLOSA-N

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Application

Polydatin, a type of polyphenolic phytoalexin, has many physiological and pharmacological effects including anti-inflammatory and anti-oxidative activities. Polydatin is an effective candidate drug for the protection of photo-inflammation. Polydatin exhibits therapeutic potential for vascular dementia, most likely due to its anti-oxidant activity and the direct protection of neurons.

Actions biochimiques/physiologiques

Stilbene found in medicinal herbs. Antioxidant, anti-inflammatory and neuroprotective.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Xingmin Wang et al.
Expert opinion on investigational drugs, 22(2), 169-179 (2012-12-18)
The aim of the study was find out whether neuronal mitochondrial injury does take place in severe shock and to explore effective therapy for severe shock. Rats were divided in the following group: sham, shock + normal saline (NS), shock
Giampietro Ravagnan et al.
Inflammation, 36(1), 26-34 (2012-09-08)
It is well known that human keratinocytes produce the anti-microbial peptide β-defensin 2. Its production is enhanced by pathogenic microorganisms or other environmental stressors. In this study, we evaluated the effect of resveratrol, a polyphenol found in several dietary source
Hong Zhang et al.
PloS one, 7(9), e46574-e46574 (2012-10-03)
Polydatin is one of main compounds in Polygonum cuspidatum, a plant with both medicinal and nutritional value. The possible hepatoprotective effects of polydatin on acute liver injury mice induced by carbon tetrachloride (CCl(4)) and the mechanisms involved were investigated. Intraperitoneal
Maria Rotches-Ribalta et al.
Pharmacological research, 66(5), 375-382 (2012-08-22)
A pharmacokinetic study of the metabolic profile of resveratrol has been performed in healthy men after moderate red wine (RW) consumption. The bioavailability of resveratrol is highly influenced by several factors such as the food matrix and, therefore, this study
Jianxin Deng et al.
Journal of molecular and cellular cardiology, 53(5), 646-656 (2012-08-28)
Polydatin (PD), a resveratrol glucoside, has recently been suggested to have cardioprotective effects against heart diseases, including ischemia-reperfusion injury and pressure-overload induced ventricular remodeling. However, the mechanisms are poorly understood. This study aims to investigate the direct effects of PD
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