Toutes les photos(1)

Key Documents

COO/COA

View All Documentation

Y0001141

Diltiazem for system suitability

Name: Diltiazem for system suitability
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

(+)-cis-Diltiazem hydrochloride, (2S,3S)-(+)-cis-3-Acetoxy-5-(2-dimethylaminoethyl)-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one hydrochloride, CRD-401

Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme

Toutes les photos(1)

About This Item

Formule empirique (notation de Hill):

C₂₂H₂₆N₂O₄S · HCl

Numéro CAS:

33286-22-5

Poids moléculaire :

450.98

Numéro Beilstein :

4228706

Numéro MDL:

MFCD00069252

Code UNSPSC :

41116107

ID de substance PubChem :

329830782

Nomenclature NACRES :

NA.24

Produits recommandés

Slide 1 of 10

1 of 10

USP

1205003

Diltiazem hydrochloride

Sigma-Aldrich

D2521

(+)-cis-Diltiazem hydrochloride

D1980000

Diltiazem hydrochloride

USP

1171706

Désacétyl diltiazem hydrochloride

Supelco

PHR2856

Diltiazem Hydrochloride

BP899

Diltiazem impurity standard

Y0001439

Diltiazem impurity F

USP

1478582

Ondansetron hydrochloride

Y0000165

Tribenoside

S0765000

Diclofenac sodium

Qualité

pharmaceutical primary standard

Famille d'API

diltiazem

Fabricant/nom de marque

EDQM

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-8°C

Chaîne SMILES

Cl.COc1ccc(cc1)[C@@H]2Sc3ccccc3N(CCN(C)C)C(=O)[C@@H]2OC(C)=O

InChI

1S/C22H26N2O4S.ClH/c1-15(25)28-20-21(16-9-11-17(27-4)12-10-16)29-19-8-6-5-7-18(19)24(22(20)26)14-13-23(2)3;/h5-12,20-21H,13-14H2,1-4H3;1H/t20-,21+;/m1./s1

Clé InChI

HDRXZJPWHTXQRI-BHDTVMLSSA-N

Informations sur le gène

human ... CACNA1C(775) , CACNA1D(776) , CACNA1F(778) , CACNA1S(779)

Vous recherchez des produits similaires ? Visite Guide de comparaison des produits

Catégories apparentées

Matériaux de référence analytiques destinés au contrôle qualité (QC) pharmaceutique

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Diltiazem for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit

Description

Tarif

Mention d'avertissement

Warning

Mentions de danger

H302

Conseils de prudence

P301 + P312 + P330

Classification des risques

Acute Tox. 4 Oral

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Faites votre choix parmi les versions les plus récentes :

Certificats d'analyse (COA)

Lot/Batch Number

Désolés, nous n'avons pas de COA pour ce produit disponible en ligne pour le moment.

Si vous avez besoin d'assistance, veuillez contacter Service Clients

Déjà en possession de ce produit ?

Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Non-ionic contrast media induces oxidative stress and apoptosis through Ca²⁺ influx in human neutrophils.

Mustafa Kayan et al.

The Journal of membrane biology, 245(12), 833-840 (2012-08-21)

Non-ionic contrast media (CM) can induce tissue kidney injury via activation of phagocytosis and oxidative stress, although the mechanisms of injury via neutrophils are not clear. We investigated the effects of CM on oxidative stress and Ca²⁺ concentrations in serum

Diltiazem hydrochloride.

B F McGraw

Drug intelligence & clinical pharmacy, 16(5), 366-370 (1982-05-01)

High-resolution mass spectrometry elucidates metabonate (false metabolite) formation from alkylamine drugs during in vitro metabolite profiling.

Joanna E Barbara et al.

Drug metabolism and disposition: the biological fate of chemicals, 40(10), 1966-1975 (2012-07-17)

In vitro metabolite profiling and characterization experiments are widely employed in early drug development to support safety studies. Samples from incubations of investigational drugs with liver microsomes or hepatocytes are commonly analyzed by liquid chromatography/mass spectrometry for detection and structural

Protective effect of diltiazem, a L-type calcium channel antagonist, on lysophosphatidylcholine-enhanced hydroxyl radical generation by MPP(+) in rat striatum.

Toshio Obata et al.

Clinical biochemistry, 46(1-2), 164-166 (2012-09-25)

The interaction between the PKC and oxygen free radicals. The present study examined the effects of lysophosphatidylcholine (LPC), an endogenous amphophilic lipid metabolite, on 1-methyl-4-phenylpyridinium ion (MPP(+))-induced hydroxyl radical (()OH) generation in rat striatum. LPC (50 μM) increased ()OH formation

Topical diltiazem vs. topical glyceril trinitrate in the treatment of chronic anal fissure: a prospective, randomized, double-blind trial.

Shahram Ala et al.

Acta gastro-enterologica Belgica, 75(4), 438-442 (2013-02-14)

Chemical sphincterotomy is a new way for the treatment of chronic anal fissure which avoids the risk of faecal incontinence associated with traditional surgical methods. The aim of this study was to compare topical Diltiazem with topical Glyceril trinitrate in

Afficher tous les articles scientifiques apparentés

Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

Contacter notre Service technique