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Y0001138

Phenazone impurity A

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

3-Methyl-1-phenyl-2-pyrazoline-5-one, 5-Methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one

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About This Item

Formule empirique (notation de Hill):
C10H10N2O
Numéro CAS:
89-25-8
Poids moléculaire :
174.20
Numéro Beilstein :
609575
Numéro MDL:
MFCD00003138
Code UNSPSC :
41116107
ID de substance PubChem :
329830780
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

phenazone

Fabricant/nom de marque

EDQM

Point d'ébullition

287 °C/265 mmHg (lit.)

Pf

126-128 °C (lit.)

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-8°C

Chaîne SMILES 

CC1=NN(C(=O)C1)c2ccccc2

InChI

1S/C10H10N2O/c1-8-7-10(13)12(11-8)9-5-3-2-4-6-9/h2-6H,7H2,1H3

Clé InChI

QELUYTUMUWHWMC-UHFFFAOYSA-N

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Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Phenazone impurity A EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H302,H319

Classification des risques

Acute Tox. 4 Oral - Eye Irrit. 2

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

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Certificats d'analyse (COA)

Lot/Batch Number

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Kentaro Deguchi et al.
Journal of neuroscience research, 92(11), 1509-1519 (2014-06-19)
Pericytes play a pivotal role in contraction, mediating inflammation and regulation of blood flow in the brain. In this study, changes of pericytes in the neurovascular unit (NVU) were examined in relation to the effects of exogenous tissue plasminogen activator
Dongqing Yuan et al.
PloS one, 9(6), e99219-e99219 (2014-06-05)
Edaravone (3-methyl-1-phenyl-2-pyrazolin-5-one), a free radical scavenger, is used for the clinical treatment of retinal injury. In this study, we investigated the protective effects of edaravone against diabetic retinal damage in the mouse. Diabetic retinopathy in the mouse was induced by
Fahui Zhao et al.
Neurosciences (Riyadh, Saudi Arabia), 19(2), 106-110 (2014-04-18)
To explore the effects of edaravone on the expression of matrix metalloproteinase-9 (MMP-9) posterior to cerebral hemorrhage, and to analyze the relationship between this expression and neurological deficit. A total of 160 basal ganglia hemorrhage patients enrolled in Dongfeng Hospital
Yu-Ichi Aoyama et al.
Journal of UOEH, 36(4), 289-294 (2014-12-17)
A 51 year old male was admitted to our hospital with sudden consciousness disturbance, global aphagia and right hemiparesis. Magnetic resonance imaging (MRI) revealed fresh infarctions in the territory of the left middle cerebral artery, and MR angiography (MRA) showed
Byeongtaek Oh et al.
Pharmaceutical research, 31(9), 2463-2478 (2014-03-26)
The nanofiber-hydrogel blend containing nitric oxide (NO) donors and reactive oxygen species (ROS) scavengers (Edaravone: EDV) was explored as an advanced strategy for stabilization of Mast cells (MCs) to achieve efficient immune-suppressive effects. Three types of nanofiber hydrogel composites (Bare-Nanofibers
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