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Key Documents

PCC030C01C

Millipore

Capsule Pellicon® avec membrane Ultracel®

pore size 30 kDa, C Screen, size 0.1 m2 , with AseptiQuik® G connectors

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About This Item

Code UNSPSC :
41104903

Matériaux

EPDM rubber seal
PPO/PS blend (core)
PPO/PS blend housing
TPE seal
Ultracel® membrane
composite regenerated cellulose (CRC) membrane
epoxy adhesive
polyester screen
polypropylene screen
polyurethane adhesive

Niveau de qualité

Stérilité

sterile; γ-irradiated

Gamme de produits

Pellicon®

Conditions de stockage

room temperature (15-30°C)

Paramètres

4-8 L/min-m2 flow rate (Feed)
50 psi max. transmembrane pressure (3.5 bar) at 4-30 °C (Forward)
75 psi max. inlet pressure (5.1 bar) at 4-30 °C

Technique(s)

ultrafiltration: suitable

Longueur

41.1 cm (16.2 in.)

Diamètre

3.8 cm (1.5 in.)

Surface de filtration

0.1 m2

Taille de l'écran

, Type C screen (coarse screen)

Taille

0.1 m2 , with AseptiQuik® G connectors

Volume

38 mL , in feed channel
68 mL , in permeate channel

Impuretés

≤5 ppm Meets TOC (in retentate effluent, after a WFI flush of 20 L/m2)

Matrice

Ultracel®

Dimension de pores

30 kDa

Plage de pH

2-13

Raccords

inlet/outlet connection (Feed: AseptiQuik® G Connector)
inlet/outlet connection (Permeate: AseptiQuik® G Connector)
inlet/outlet connection (Retentate: AseptiQuik® G Connector)

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Description générale

The Pellicon® Capsule is the first of its kind -- a true single-use TFF device that comes ready to process in minutes. Self-contained, it employs an easy-to-use, holderless format and is supplied sterilized by irradiation.

Application

Concentration, Diafiltration, Buffer exchange, Protein purification

Caractéristiques et avantages

Plug ′n play, holderless design - easy to install, safe to remove
Gamma sterilized and preseravtive-free - ready to process in minutes
True single-use, self-contained capusle - fast, safe, and flexible batch turnaround
Proven Ultracel® membrane and C screen - high recovery, superior mass transfer, solvent resistance
Pellicon® TFF proven performance - true linear scalability within Pellicon® TFF families

Conditionnement

A foam pouch is inserted over the end caps on both ends of the capsule which is then double-bagged and vacuum sealed. The double-bagged capsule is then placed on a tray and individually boxed.

Autres remarques

The Emprove® Program complements the product portfolio through

Comprehensive documentation to support qualification, risk assessment and process optimization needs.
Consolidation of product specific testing, quality and regulatory information to simplify compliance requirements.
Convenient 24/7 access to up-to-date product information.

Informations légales

AseptiQuik is a registered trademark of Colder Products Company
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
Pellicon is a registered trademark of Merck KGaA, Darmstadt, Germany
ULTRACEL is a registered trademark of Merck KGaA, Darmstadt, Germany

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Articles

Find best practices for using Pellicon® Capsules in ADC processing as well as data from two studies using Pellicon® Capsules and Pellicon® cassettes in the ADC manufacturing process.

Find best practices for using Pellicon® Capsules in ADC processing as well as data from two studies using Pellicon® Capsules and Pellicon® cassettes in the ADC manufacturing process.

Find best practices for using Pellicon® Capsules in ADC processing as well as data from two studies using Pellicon® Capsules and Pellicon® cassettes in the ADC manufacturing process.

Find best practices for using Pellicon® Capsules in ADC processing as well as data from two studies using Pellicon® Capsules and Pellicon® cassettes in the ADC manufacturing process.

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Contenu apparenté

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Learn more on mAb downstream processing, more specifically concentration and diafiltration, and the relevant associated products.

Learn more on mAb downstream processing, more specifically concentration and diafiltration, and the relevant associated products.

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