258822

4-Methylmorpholine N-oxide solution

50 wt. % in H₂O

• Synonyme(s) : NMMO solution, NMO solution, NSC 73198, NSC 82153
• Formule empirique (notation de Hill): C₅H₁₁NO₂
• Numéro CAS: 7529-22-8
• Poids moléculaire : 117.15
• Numéro MDL: MFCD00005947
• Code UNSPSC : 12352005
• ID de substance PubChem : 24855662
• Nomenclature NACRES : NA.22

Propriétés

• Forme: liquid
• Pertinence de la réaction: reagent type: oxidant
• Concentration: 50 wt. % in H₂O
• Indice de réfraction: n20/D 1.4201
• pH: 9.00 ( in neat)
• Point d'ébullition: 118.5 °C
• Pf: −20 °C
• Densité: 1.13 g/mL at 25 °C
• Groupe fonctionnel: ether
• Température de stockage: 2-8°C
• Chaîne SMILES: C[N+]1([O-])CCOCC1
• InChI: 1S/C5H11NO2/c1-6(7)2-4-8-5-3-6/h2-5H2,1H3
• Clé InChI: LFTLOKWAGJYHHR-UHFFFAOYSA-N

Description

Application

• 4-Methylmorpholine N-oxide (NMO) is widely used as a co-oxidant to regenerate osmium tetroxide (OsO₄) catalyst during dihydroxylation of alkenes.
• In the presence of catalytic amounts of tetra-n-propylammonium perruthenate (TPAP), NMO oxidizes secondary amines to the corresponding imines.
• 4-Methylmorpholine N-oxide solution can be used to oxidize activated primary halides to aldehydes and secondary halides to ketones, respectively.
• It can also be used to promote stereoselective intermolecular Pauson-Khand reaction for the synthesis of cyclopentenones.

Oxidant for synthesis of novel organic polymer - inorganic hybrid for use as a catalyst for asymmetrical epoxidation

Reagent or Reactant for:

• Cyclocondensation and cyclization in the enantioselective synthesis of oxazolomycin A
• Wharton rearrangement and stereoselective dihydroxylation reactions
• Reduction of amine N-oxides by diboron reagents
• Synthesis of polysaccharide blend fibers
• Synthesis of cellulose / modified nano-SiO2 composite packaging films
• Copper-catalyzed oxidative coupling for preparation of propargylamines

Used as a pretreatment for techno-economical study of ethanol and biogas production from spruce wood

Informations sur la sécurité

• Pictogrammes: GHS08
• Mention d'avertissement: Warning
• Mentions de danger: H361f
• Conseils de prudence: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Classification des risques: Repr. 2
• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Équipement de protection individuelle: Eyeshields, Gloves, type ABEK (EN14387) respirator filter