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Staphylococcus aureus

buffered aqueous suspension, Wood 46 strain

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About This Item

Code UNSPSC :
12352202
Nomenclature NACRES :
NA.81
Le tarif et la disponibilité ne sont pas disponibles actuellement.

Source biologique

Staphylococcus aureus

Stérilité

Not processed or packaged aseptically

Forme

buffered aqueous suspension

Composition

Cell suspension, ~10% wet weight/volume

Température de stockage

2-8°C

Description générale

Staphylococcus aureus Wood 46 is protein A deficient and spa negative.[1] It shares 98% to 99% genome identity with S.aureus[1] and shows a lower surface expression of cell wall-associated protein A.[2]

Application

(Not intended for use as a starter culture.)
Staphylococcus aureus has been used:
  • to mimic infection and induce fever in Pekin duck[3]
  • to test its effect on hemocyte morphology in hemolymph samples from beetle Tenebrio molitor larva[4]
  • in the antibacterial activity and minimum inhibitory concentration (MIC) assay with gedunin and 7-deacetoxy-7αhydroxygedunin potassium salt [5]

Wood 46, a non-protein A producing S. aureus strain[6], prepared by the same method as P7155 (Protein A, crude cell suspension-Cowan strain), may be used as a control in protein A-immunoglobulin binding studies.

Actions biochimiques/physiologiques

Staphylococcus aureus Wood 46 displays reduced virulence compared to the S. aureus.[1] This isolate is useful in understanding protein A role in pathogenesis and virulence.[2]

Forme physique

Formalin-fixed crude cell suspension of essentially non-viable S. aureus (Wood 46 strain) in 0.05 M potassium phosphate buffer, pH 7.5, containing 0.2% sodium azide

Notes préparatoires

Produced in pure culture.

Remarque sur l'analyse

This strain binds less than 10% of the rabbit IgG bound by P 7155 as assayed by a modification of the method of Kessler[7].

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number
0000268284
0000252791
0000268284
0000252791
113H6809

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Manasi Balachandran et al.
Genome announcements, 5(13) (2017-04-01)
Here, we report the first complete genome sequence of the Staphylococcus aureus strain Wood 46. Wood 46 has played an important role in understanding the virulence and pathogenesis of S. aureus infections. This report will assist efforts in vaccine development against
Manasi Balachandran et al.
PloS one, 12(8), e0183913-e0183913 (2017-09-01)
Protein A in Staphylococcus aureus is encoded by the spa (staphylococcal protein A) gene and binds to immunoglobulin (Ig). The S. aureus strain Wood 46 has been variously reported as protein A-deficient and/or spa negative and used as a control
Arkadiusz Urbański et al.
Scientific reports, 12(1), 17277-17277 (2022-10-15)
Tachykinins (TKs) are a group of conserved neuropeptides. In insects, tachykinin-related peptides (TRPs) are important modulators of several functions such as nociception and lipid metabolism. Recently, it has become clear that TRPs also play a role in regulating the insect
Synthetic modification of gedunin and comparative antibacterial activity of gedunin and 7-deacetoxy-7alpha-hydroxygedunin potassium salt
Okhale SE, et al.
African Journal of Pure and Applied Chemistry, 6(14), 183-189 (2012)
S W Kessler
Journal of immunology (Baltimore, Md. : 1950), 117(5 Pt 1), 1482-1490 (1976-11-01)
Procedures are detailed for the rapid isolation of representative cell membrane antigens with protein A-bearing staphylococci as an adsorbent for IgG antibodies complexed with the antigens. Cell surface membrane proteins were radioiodinated and solubilized in nonionic detergent. Specific antisera were
Afficher tous les articles scientifiques apparentés

Questions

  1. Hello, I'm wondering if this "Staphylococcus aureus, wood 46 strain" is deactivated or not. Additionally, do you have the corresponding aptamer or antibody of this strain?

    1 réponse

    1. This product is a formalin-fixed crude cell suspension of essentially non-viable S. aureus in 0.05 M potassium phosphate buffer containing 0.2% sodium azide. Currently, there is no corresponding aptamer or antibody for the Wood 46 Strain.

      Utile ?

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