F7016
Flumequine
≥97.0% (HPLC)
Synonyme(s) :
9-Fluoro-5-methyl-1-oxo-1,5,6,7-tetrahydropyrido[3,2,1-ij]quinoline-2-carboxylic acid
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A propos de cet article
Formule empirique (notation de Hill) :
C14H12FNO3
Numéro CAS:
Poids moléculaire :
261.25
UNSPSC Code:
51102829
NACRES:
NA.85
PubChem Substance ID:
EC Number:
255-962-6
Beilstein/REAXYS Number:
490724
MDL number:
assay
≥97.0% (HPLC)
form
powder
color
white to off-white
antibiotic activity spectrum
Gram-negative bacteria, Gram-positive bacteria
mode of action
DNA synthesis | interferes, enzyme | inhibits
SMILES string
CC1CCc2cc(F)cc3C(=O)C(=CN1c23)C(O)=O
InChI
1S/C14H12FNO3/c1-7-2-3-8-4-9(15)5-10-12(8)16(7)6-11(13(10)17)14(18)19/h4-7H,2-3H2,1H3,(H,18,19)
InChI key
DPSPPJIUMHPXMA-UHFFFAOYSA-N
General description
Chemical structure: fluoroquinolone
Biochem/physiol Actions
Flumequine inhibits topoisomerases, which are needed for the transcription and replication of bacterial DNA. The inhibition of the topoisomerases results in strand breakage of the bacterial chromosome, supercoiling, and resealing. Therefore, DNA replication and transcription is inhibited .
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Classe de stockage
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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