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S0150000

Salbutamol hemisulfate salt

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

Salbutamol hemisulfate salt, α1-[(tert-Butylamino)methyl]-4-hydroxy-1,3-benzenedimethanol hemisulfate salt, Albuterol sulfate

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About This Item

Formule empirique (notation de Hill):
C13H21NO3 · 0.5H2SO4
Numéro CAS:
51022-70-9
Poids moléculaire :
288.35
Numéro MDL:
MFCD00055200
Code UNSPSC :
41116107
ID de substance PubChem :
329824415
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

albuterol, salbutamol

Fabricant/nom de marque

EDQM

Application(s)

pharmaceutical (small molecule)

Format

neat

Chaîne SMILES 

OS(O)(=O)=O.CC(C)(C)NCC(O)c1ccc(O)c(CO)c1.CC(C)(C)NCC(O)c2ccc(O)c(CO)c2

InChI

1S/2C13H21NO3.H2O4S/c2*1-13(2,3)14-7-12(17)9-4-5-11(16)10(6-9)8-15;1-5(2,3)4/h2*4-6,12,14-17H,7-8H2,1-3H3;(H2,1,2,3,4)

Clé InChI

BNPSSFBOAGDEEL-UHFFFAOYSA-N

Informations sur le gène

human ... ADRB2(154)

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Catégories apparentées

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Salbutamol sulfate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

Y0000034

Salbutamol impurity G, European Pharmacopoeia (EP) Reference Standard

Y0000030

Salbutamol impurity B, European Pharmacopoeia (EP) Reference Standard

Y0000031

Salbutamol impurity F, European Pharmacopoeia (EP) Reference Standard

Y0000071

Salbutamol impurity D, European Pharmacopoeia (EP) Reference Standard

Y0000032

Salbutamol impurity I, European Pharmacopoeia (EP) Reference Standard

S0100000

Salbutamol, European Pharmacopoeia (EP) Reference Standard

Y0001186

Salbutamol impurity J, European Pharmacopoeia (EP) Reference Standard

Y0001288

Salbutamol hemisulfate salt, European Pharmacopoeia (EP) Reference Standard

1012633

Salbutamol hemisulfate salt, United States Pharmacopeia (USP) Reference Standard

1358784

Levalbuterol hydrochloride, United States Pharmacopeia (USP) Reference Standard

1012600

Salbutamol, United States Pharmacopeia (USP) Reference Standard

1012644

Albuterol Related Compound A, United States Pharmacopeia (USP) Reference Standard

1012655

Albuterol Related Compound B, United States Pharmacopeia (USP) Reference Standard

1012689

Albuterol Related Compound E, United States Pharmacopeia (USP) Reference Standard

BP451

Salbutamol, British Pharmacopoeia (BP) Reference Standard

BP302

Salbutamol hemisulfate salt, British Pharmacopoeia (BP) Reference Standard

PHR1960

Salbutamol Impurity D, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2040

Albuterol Related Compound B, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1961

Salbutamol Impurity G, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1962

Salbutamol impurity I, Pharmaceutical Secondary Standard; Certified Reference Material

BP712

Salbutamol aldehyde impurity, British Pharmacopoeia (BP) Reference Standard

BP192

2-tert-Butylamino-1-(4-hydroxy-3-methylphenyl)ethanol sulfate, British Pharmacopoeia (BP) Reference Standard

BP852

Salbutamol impurity B, British Pharmacopoeia (BP) Reference Standard

BP704

Salbutamol ketone impurity, British Pharmacopoeia (BP) Reference Standard

PHR2106

4-[2-[(1,1-Dimethylethyl)amino]ethyl]-2-methylphenol, Pharmaceutical Secondary Standard; Certified Reference Material

PHR9050

4-[2-(tert-Butylamino)-1-methoxyethyl]-2-(hydroxymethyl)phenol, reference material, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

PHR9071

4-[2-[Benzyl(tert-butyl)amino]-1-hydroxyethyl]-2-(hydroxymethyl)phenol, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

1012564

Albuterol Related Compound I, United States Pharmacopeia (USP) Reference Standard

PHR2332

Methyl5-[2-[benzyl(tert-butyl)amino]acetyl]-2-hydroxybenzoate hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material

Pictogrammes

Health hazardExclamation mark
GHS08,GHS07

Mention d'avertissement

Warning

Mentions de danger

H317,H351,H361fd

Classification des risques

Carc. 2 - Repr. 2 - Skin Sens. 1

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

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Consulter la Bibliothèque de documents

B Padhukasahasram et al.
The pharmacogenomics journal, 14(4), 365-371 (2014-01-15)
Inhaled short-acting beta-agonist (SABA) medication is commonly used in asthma patients to rapidly reverse airway obstruction and improve acute symptoms. We performed a genome-wide association study of SABA medication response using gene-based association tests. A linear mixed model approach was
Huan Wang et al.
Biosensors & bioelectronics, 49, 14-19 (2013-05-28)
A multiplexed electrochemical biosensor has been developed for fast and sensitive detection of ractopamine (RAC), salbutamol (SAL) and clenbuterol (CLB) based on reduced graphene oxide (rGO) and silver-palladium alloy nanoparticles (AgPd NPs). In this paper, rGO with high conductivity was
Ashley Woodcock et al.
Chest, 144(4), 1222-1229 (2013-07-13)
The combination of fluticasone furoate (FF), a novel inhaled corticosteroid (ICS), and vilanterol (VI), a long-acting β2 agonist, is under development as a once-daily treatment of asthma and COPD. The aim of this study was to compare the efficacy of
Khalid Alansari et al.
Pediatrics, 132(4), e810-e816 (2013-09-18)
Determine whether dexamethasone treatment added to salbutamol reduces time to readiness for discharge in patients with bronchiolitis and possible asthma. We compared efficacy and safety of dexamethasone, 1 mg/kg, then 0.6 mg/kg for 4 more days, with placebo for acute
Mariam Mamlouk et al.
The Journal of asthma : official journal of the Association for the Care of Asthma, 50(4), 334-341 (2013-02-15)
The aim of this study was to characterize the permeability kinetics of salbutamol sulfate, a commonly used β2-agonist in the treatment of asthma exacerbation, across Calu-3 respiratory epithelial cell monolayers in the presence of non-steroidal anti-inflammatory drugs (NSAIDs), as they
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