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C2400000

Clonidine hydrochloride

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

2-(2,6-Dichloroanilino)-2-imidazoline hydrochloride

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About This Item

Formule empirique (notation de Hill):
C9H9Cl2N3 · HCl
Numéro CAS:
4205-91-8
Poids moléculaire :
266.55
Numéro Beilstein :
4163525
Numéro MDL:
MFCD00036705
Code UNSPSC :
41116107
ID de substance PubChem :
329775001
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

clonidine

Fabricant/nom de marque

EDQM

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-8°C

Chaîne SMILES 

Cl[H].Clc1cccc(Cl)c1NC2=NCCN2

InChI

1S/C9H9Cl2N3.ClH/c10-6-2-1-3-7(11)8(6)14-9-12-4-5-13-9;/h1-3H,4-5H2,(H2,12,13,14);1H

Clé InChI

ZNIFSRGNXRYGHF-UHFFFAOYSA-N

Informations sur le gène

human ... ADRA2A(150) , ADRA2B(151) , ADRA2C(152)

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Catégories apparentées

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Clonidine hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

Y0000801

Clonidine impurity B, European Pharmacopoeia (EP) Reference Standard

1140407

Clonidine hydrochloride, United States Pharmacopeia (USP) Reference Standard

1140418

Clonidine Related Compound A, United States Pharmacopeia (USP) Reference Standard

1140393

Clonidine, United States Pharmacopeia (USP) Reference Standard

1140429

Clonidine Related Compound B, United States Pharmacopeia (USP) Reference Standard

1041609

Apraclonidine hydrochloride, United States Pharmacopeia (USP) Reference Standard

BP085

Clonidine hydrochloride, British Pharmacopoeia (BP) Reference Standard

PHR3177

Apraclonidine Hydrochloride, pharmaceutical secondary standard, certified reference material

Pictogrammes

Skull and crossbones
GHS06

Mention d'avertissement

Danger

Mentions de danger

H301,H330

Classification des risques

Acute Tox. 1 Inhalation - Acute Tox. 3 Oral

Code de la classe de stockage

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

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Paula E Park et al.
Addiction biology, 20(2), 275-284 (2013-12-18)
Opioids represent effective drugs for the relief of pain, yet chronic opioid use often leads to a state of increased sensitivity to pain that is exacerbated during withdrawal. A sensitization of pain-related negative affect has been hypothesized to closely interact
Yanyan Qiu et al.
Scientific reports, 4, 6605-6605 (2014-10-14)
This study examined whether a novel imidazoline I₂ receptor ligand CR4056 could serve as a discriminative stimulus and whether it shares similar discriminative stimulus effects with other reported I₂ receptor ligands. Eight male Sprague-Dawley rats were trained to discriminate 10.0 mg/kg
Craige C Wrenn et al.
Neuroscience letters, 585, 109-113 (2014-11-30)
Fragile X syndrome (FXS), a disorder caused by a mutation in the FMR1 gene, is often associated with Attention Deficit Hyperactivity Disorder (ADHD). Common treatments for the hyperactivity often seen in ADHD involve the use of stimulants and α2-adrenergic agonists.
Kalpashri Kesavan et al.
Respiratory physiology & neurobiology, 201, 93-100 (2014-07-11)
Sedative-analgesics are often given to newborn infants and are known to affect many components of the autonomic nervous system. While morphine is most frequently used, α-2 adrenergic receptor agonists are being increasingly used in this population. Alpha-2 adrenergic receptors agonists
Jonathan W Pinkston et al.
Behavioural pharmacology, 25(7), 629-636 (2014-08-15)
Under many circumstances, reinforcer magnitude appears to modulate the rate-dependent effects of drugs such that when schedules arrange for relatively larger reinforcer magnitudes rate dependency is attenuated compared with behavior maintained by smaller magnitudes. The current literature on resistance to
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