761435

cataCXium^® A Pd G3

95%

• Synonyme(s) : Mesylate[(di(1-adamantyl)-n-butylphosphine)-2-(2′-amino-1,1′-biphenyl)]palladium(II), [(Di(1-adamantyl)-butylphosphine)-2-(2′-amino-1,1′-biphenyl)]palladium(II) methanesulfonate, cataCXium-A-Pd-G3
• Formule empirique (notation de Hill): C₃₇H₅₂NO₃PPdS
• Numéro CAS: 1651823-59-4
• Poids moléculaire : 728.27
• Code UNSPSC : 12352300
• ID de substance PubChem : 329766937
• Nomenclature NACRES : NA.22

Propriétés

• Niveau de qualité: 100
• Pureté: 95%
• Forme: solid
• Caractéristiques: generation 3
• Capacité de réaction: reaction type: Buchwald-Hartwig Cross Coupling Reaction; reaction type: Heck Reaction; reaction type: Hiyama Coupling; reaction type: Negishi Coupling; reaction type: Sonogashira Coupling; reaction type: Stille Coupling; reaction type: Suzuki-Miyaura Coupling
• Pertinence de la réaction: reagent type: catalyst; reaction type: Cross Couplings
• Impuretés: ≤3% acetone
• Pf: 196-241 °C (decomposition)
• Groupe fonctionnel: phosphine
• Chaîne SMILES: CS(=O)(=O)O[Pd]c1ccccc1-c2ccccc2N.CCCCP([C@@]34C[C@@H]5C[C@@H](C[C@@H](C5)C3)C4)[C@@]67C[C@@H]8C[C@@H](C[C@@H](C8)C6)C7
• InChI: 1S/C24H39P.C12H10N.CH4O3S.Pd/c1-2-3-4-25(23-11-17-5-18(12-23)7-19(6-17)13-23)24-14-20-8-21(15-24)10-22(9-20)16-24;13-12-9-5-4-8-11(12)10-6-2-1-3-7-10;1-5(2,3)4;/h17-22H,2-16H2,1H3;1-6,8-9H,13H2;1H3,(H,2,3,4);/q;;;+1/p-1/t17-,18+,19-,20-,21+,22-,23-,24-;;;
• Clé InChI: REYVZCOGMIXVNX-DVBMAMJVSA-M

Description

Application

cataCXium^® A Pd G3 is a Buchwald third-generation precatalyst that can be used in:

• Direct ortho-arylation of pyridinecarboxylic acids.
• Catalyzing Suzuki–Miyaura cross-coupling in the synthesis of 1-heteroaryl-3-azabicyclo[3.1.0]hexanes.
• Palladium-catalyzed carbonylative carboperfluoroalkylation of alkynes.
• Suzuki–Miyaura coupling reaction of geminal bis(boryl)cyclopropanes in the synthesis of various gem-disubstituted cyclopropanes.
• Boroperfluoroalkylation of terminal alkynes.
• Copper-free Sonogashira coupling reaction of aromatic halides with alkynes to form C-C bond.
• Suzuki cross-coupling between organotrifluoroborate and aryl halides.

For small scale and high throughput uses, product is also available as ChemBeads (928305)

Informations légales

cataCXium is a registered trademark of Umicore AG & Co. KG

Informations sur la sécurité

• Code de la classe de stockage: 13 - Non Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable