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Merck

SCNN1B

sodium channel, non-voltage-gated 1, beta subunit

Synonymes:
BESC1, ENaCb, ENaCbeta, SCNEB
Espèce(s):
Human SCNN1B (6338), Mouse Scnn1b (20277), Rat Scnn1b (24767), chicken SCNN1B (427673), dog SCNN1B (489972), Horse SCNN1B (100069008), domestic cat SCNN1B (101099767), cow SCNN1B (533355), sheep SCNN1B (100170325), Goat SCNN1B (100861026) ...Plus
ID UniProtKB:
P51168, C5HTZ2, O60891, Q96KG2, Q9UJ32, Q9UMU5
ID du gène:
  • Human(6338) Summary: Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the beta subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), and Liddle syndrome. [provided by RefSeq, Apr 2009]
  • Mouse(20277) sodium channel, nonvoltage-gated 1 beta
  • Rat(24767) sodium channel, nonvoltage-gated 1, beta
  • chicken(427673) sodium channel, non-voltage-gated 1, beta subunit
  • dog(489972) sodium channel, non-voltage-gated 1, beta subunit
  • Horse(100069008) sodium channel, non-voltage-gated 1, beta subunit
  • domestic cat(101099767) sodium channel, non-voltage-gated 1, beta subunit
  • cow(533355) sodium channel, nonvoltage-gated 1, beta
  • sheep(100170325) sodium channel, non-voltage-gated 1, beta subunit
  • Goat(100861026) sodium channel, non-voltage-gated 1, beta subunit
  • Domestic Rabbit(100009564) sodium channel, non-voltage-gated 1, beta subunit
  • domestic guinea pig(100270805) sodium channel, nonvoltage-gated 1 beta
  • naked mole-rat(101717352) sodium channel, non-voltage-gated 1, beta subunit

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Antibodies

Numéro du produit
Description
Espèces réactives
Application
HPA015612
Anti-SCNN1B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
western blot
SAB5200106
Anti-SCNN1B antibody produced in rabbit, 1 mg/mL, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
immunoprecipitation (IP)
western blot
SAB5201788
Monoclonal Anti-ENaC beta antibody produced in mouse, clone 7B8,
Espèces réactives
mouse
Application
immunohistochemistry
western blot
AB3532P
Anti-Epithelial Sodium Channel-β Antibody, Chemicon®, from rabbit,
Espèces réactives
mouse, rat
Application
ELISA
western blot
SAB5201806
Monoclonal Anti-ENaC beta antibody produced in mouse, clone 16E4,
Espèces réactives
mouse
Application
western blot

Small Molecule - Blocker

Numéro du produit
Description
Espèce(s)
T4143
Triamterene, ≥99%,
Espèce(s)
human
PHR1722
Triamterene, Pharmaceutical Secondary Standard; Certified Reference Material,
Espèce(s)
human
1680007
Triamterene, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human
Y0000837
Triamterene, European Pharmacopoeia (EP) Reference Standard,
Espèce(s)
human
BP340
Triamterene, British Pharmacopoeia (BP) Reference Standard,
Espèce(s)
human

Small Molecule - Inhibitor

Numéro du produit
Description
Espèce(s)
B2417
Benzamil hydrochloride hydrate, ≥98% (HPLC),
Espèce(s)
mouse, rat, human
P203
Phenamil methanesulfonate salt, solid,
Espèce(s)
mouse, rat, human
A5585
5-(N-Methyl-N-isobutyl)­amiloride, ≥98% (TLC), powder,
Espèce(s)
mouse, rat, human
A4562
5-(N,N-Dimethyl)amiloride hydrochloride, ,
Espèce(s)
rat, mouse, human
A9561
5-(N,N-Hexamethylene)amiloride, ,
Espèce(s)
rat, human, mouse

esiRNA

Numéro du produit
Description
Espèce(s)
EHU066451
MISSION® esiRNA, targeting human SCNN1B,
Espèce(s)
human