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Merck

47868

Supelco

D-Biotin

analytical standard

Sinónimos:

Biotina, D-Biotina, Bios II, Coenzima R, Vitamina H, Vitaminas B7

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About This Item

Fórmula empírica (notación de Hill):
C10H16N2O3S
Número de CAS:
Peso molecular:
244.31
Beilstein:
86838
Número CE:
Número MDL:
Código UNSPSC:
12164500
ID de la sustancia en PubChem:

grado

analytical standard

Características

standard type water soluble vitamin

envase

ampule of 100 mg

técnicas

HPLC: suitable
gas chromatography (GC): suitable

mp

231-233 °C (lit.)

aplicaciones

pharmaceutical (small molecule)
vitamins, nutraceuticals, and natural products

formato

neat

temp. de almacenamiento

2-8°C

cadena SMILES

[H][C@]12CS[C@@H](CCCCC(O)=O)[C@@]1([H])NC(=O)N2

InChI

1S/C10H16N2O3S/c13-8(14)4-2-1-3-7-9-6(5-16-7)11-10(15)12-9/h6-7,9H,1-5H2,(H,13,14)(H2,11,12,15)/t6-,7-,9-/m0/s1

Clave InChI

YBJHBAHKTGYVGT-ZKWXMUAHSA-N

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Descripción general

D-biotin is water soluble vitamin, which belongs to the B-complex group of vitamins. It generally serves as a covalently-bound coenzyme for several carboxylases. It is an essential micronutrient required for normal cell functions and can be obtained both dietary sources as well as gut microbiota.

Aplicación

D-Biotin may be used as an analytical reference standard for the quantification of the analyte in food samples using high-performance liquid chromatography (HPLC)/avidin-binding assay.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)


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Certificados de análisis (COA)

Lot/Batch Number

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Pharmacological Effects of Biotin in Animals
L R-N and C F-M
Mini-Reviews in Medicinal Chemistry, 17, 529-529 (2017)
Determination of the biotin content of select foods using accurate and sensitive HPLC/avidin binding
Staggs GC, et al.
Journal of food composition and analysis, 17(6), 767-776 (2004)
Lipopolysaccharide inhibits colonic biotin uptake via interference with membrane expression of its transporter: a role for a casein kinase 2-mediated pathway
Lakhan R and Said.MS
American Journal of Physiology. Cell Physiology, 312, C376-C384 (2017)
Tuan V Bui et al.
Neuron, 78(1), 191-204 (2013-04-16)
Accurate motor performance depends on the integration in spinal microcircuits of sensory feedback information. Hand grasp is a skilled motor behavior known to require cutaneous sensory feedback, but spinal microcircuits that process and relay this feedback to the motor system
Naruo Nikoh et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(28), 10257-10262 (2014-07-02)
Obligate insect-bacterium nutritional mutualism is among the most sophisticated forms of symbiosis, wherein the host and the symbiont are integrated into a coherent biological entity and unable to survive without the partnership. Originally, however, such obligate symbiotic bacteria must have

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