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Merck

47865-U

Supelco

Nicotinamide (Niacinamide)

analytical standard

Sinónimos:

Nicotinamide

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About This Item

Fórmula empírica (notación de Hill):
C6H6N2O
Número de CAS:
Peso molecular:
122.12
Beilstein:
383619
Número CE:
Número MDL:
Código UNSPSC:
85151701
ID de la sustancia en PubChem:
NACRES:
NA.24

grado

analytical standard

Nivel de calidad

CofA

current certificate can be downloaded

Características

standard type water soluble vitamin

envase

ampule of 1000 mg

técnicas

HPLC: suitable
gas chromatography (GC): suitable

mp

128-131 °C (lit.)

aplicaciones

clinical testing

formato

neat

temp. de almacenamiento

2-30°C

cadena SMILES

NC(=O)c1cccnc1

InChI

1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)

Clave InChI

DFPAKSUCGFBDDF-UHFFFAOYSA-N

Información sobre el gen

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Descripción general

Nicotinamide (Niacinamide), belonging to the class of water-soluble B vitamins, is typically produced from nicotinic acid (vitamin B3). It is found as a component of food products. It has been suggested for the treatment of pellagra, psoriasis, schizophrenia, and type I diabetes. It also exhibits anti-inflammatory activity.

Aplicación

Nicotinamide (Niacinamide) may be used as a reference standard for the determination of the analyte in pharmaceutical formulations and biological fluids by chromatography, UV-visible spectrophotometry and multivariate analysis.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Acciones bioquímicas o fisiológicas

Nicotinamide is an amide derivative of vitamin B3 and a PARP inhibitor

Productos recomendados

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Pictogramas

Exclamation mark

Palabra de señalización

Warning

Frases de peligro

Clasificaciones de peligro

Eye Irrit. 2

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

302.0 °F - closed cup

Punto de inflamabilidad (°C)

150 °C - closed cup

Equipo de protección personal

dust mask type N95 (US), Eyeshields, Gloves


Choose from one of the most recent versions:

Certificados de análisis (COA)

Lot/Batch Number

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Visite la Librería de documentos

Industrial application of green chromatography?I. Separation and analysis of niacinamide in skincare creams using pure water as the mobile phase
Yang Y, et al.
Talanta, 84(1), 169-174 (2011)
Evaluation of analytical tools and multivariate methods for quantification of co-former crystals in ibuprofen-nicotinamide co-crystals
Soares FLF and Carneiro RL
Journal of Pharmaceutical and Biomedical Analysis, 89, 166-175 (2014)
Development of a validated HPLC method for the determination of B-complex vitamins in pharmaceuticals and biological fluids after solid phase extraction
Chatzimichalakis PF, et al.
Journal of Separation Science, 27(14), 1181-1188 (2004)
Nicotinamide
European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 14(4), 3145-3146 (2017)
Efrat Resnick et al.
Journal of the American Chemical Society, 141(22), 8951-8968 (2019-05-08)
Covalent probes can display unmatched potency, selectivity, and duration of action; however, their discovery is challenging. In principle, fragments that can irreversibly bind their target can overcome the low affinity that limits reversible fragment screening, but such electrophilic fragments were

Artículos

Learn to separate and quantify B vitamins and preservatives in capsules with HPLC-UV and Purospher® STAR RP-8 column. Validated for precision.

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