SRP6553

CIRBP/Cold-inducible RNA-binding protein human

recombinant, expressed in E. coli, ≥90% (SDS-PAGE)

• Sinónimos: A18HNRNP, CIRP
• Código UNSPSC: 12352202
• NACRES: NA.32

Propiedades

• origen biológico: human
• recombinante: expressed in E. coli
• Ensayo: ≥90% (SDS-PAGE)
• Formulario: lyophilized
• mol peso: 20.5 kDa
• envase: pkg of 1 mg; pkg of 20 μg
• impurezas: ≤1 EU/μg endotoxin (LAL test)
• Nº de acceso UniProt: Q14011
• Condiciones de envío: wet ice
• temp. de almacenamiento: −70°C
• Información sobre el gen: human ... CIRBP(1153)

Descripción

Descripción general

CIRBP, also known as cold-inducible RNA-binding protein, plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. CIRBP responds to a wide array of cellular stresses, including short wavelength ultraviolet light (UVC), at the transcriptional and post-translational level. It acts as a translational activator. CIRBP can bind the 3′untranslated region of specific transcripts to stabilize them and facilitate their transport to ribosomes for translation. CIRBP affects NF-κB signaling as opposed to IL1B mRNA stability directly.

Forma física

Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 0.25 M Imidazole, 20% glycerol.

Reconstitución

Detailed reconstitution instructions are sent along with the product

Información de seguridad

• Pictogramas: GHS08,GHS07
• Palabra de señalización: Danger
• Frases de peligro: H315,H319,H360D
• Consejos de prudencia: P202 - P264 - P280 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Clasificaciones de peligro: Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2
• Código de clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable