SRP4304

NGF-beta from mouse

recombinant, expressed in E. coli, ≥98% (SDS-PAGE)

• Sinónimos: Nerve Growth Factor β, Ngf, Ngfb
• Código UNSPSC: 12352202
• NACRES: NA.32

Propiedades

• origen biológico: mouse
• recombinante: expressed in E. coli
• Ensayo: ≥98% (SDS-PAGE)
• Formulario: lyophilized
• potencia: 0.2 ng/mL ED₅₀
• mol peso: ~13.4 kDa
• envase: pkg of 20 μg
• impurezas: endotoxin, tested
• Nº de acceso NCBI: P01139
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• Información sobre el gen: mouse ... Ngf(18049)

Descripción

Descripción general

Nerve growth factor-β (NGF-β) belongs to the neurotrophin family.[1] The active form of human NGF-β is a homodimer, non-glycosylated chain.[2]

Acciones bioquímicas o fisiológicas

Nerve growth factor-β (NGF-β) is a potent neurotrophic factor that supports the growth and survivability of nerve and/or glial cells.[1] It brings pro-survival effects with the help of receptor tyrosine kinase TrkA.[3] NGF-β is associated with diabetic neuropathy and ischemic heart disease.[1] It is also involved in airway nerve system.[4] NGF-β is also responsible for the pain which is linked with osteoarthritis (OA).[5] It is involved in liver fibrosis, carcinogenesis, angiogenesis and cholangiocyte proliferation.[6]

Forma física

Lyophilized without any additives.

Reconstitución

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.

Reconstitute in water to a concentration of 0.1-1.0 mg/mL containing 1% HSA or BSA. The solution can be diluted into other aqueous buffers and stored at 4°C for 2-7 days or store at –20°C for future use.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable