SML2397

Dooku1

≥98% (HPLC), eIF4E inhibitor, powder

• Sinónimos: 2-((2,6-dichlorobenzyl)thio)-5-(1H-pyrrol-2-yl)-1,3,4-oxadiazole
• Fórmula empírica (notación de Hill): C₁₃H₉Cl₂N₃OS
• Número CAS: 2253744-54-4
• Peso molecular: 326.20
• UNSPSC Code: 12352200
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder

Propiedades

• Nombre del producto: Dooku1, ≥98% (HPLC)
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: −20°C
• SMILES string: ClC(C=CC=C1Cl)=C1CSC2=NN=C(C3=CC=CN3)O2
• InChI: 1S/C13H9Cl2N3OS/c14-9-3-1-4-10(15)8(9)7-20-13-18-17-12(19-13)11-5-2-6-16-11/h1-6,16H,7H2
• InChI key: MNPOBXLPCWFONX-UHFFFAOYSA-N

Descripción

Biochem/physiol Actions

Dooku1, an analog of Yoda1, is a potent and selective antagonist of the mechanosensitive Piezo1 channel that inhibits endogenous Yoda1-activated channels. Dooku1 inhibits relaxation of relaxation of aorta caused by Yoda1.

potent and selective antagonist of the mechanosensitive Piezo1 channel that inhibits endogenous Yoda1-activated channels

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable