SML1804

AM4113

≥98% (HPLC)

• Sinónimos: 5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide
• Fórmula empírica (notación de Hill): C₁₇H₁₂Cl₃N₃O
• Número CAS: 614726-85-1
• Peso molecular: 380.66
• UNSPSC Code: 12352200
• PubChem Substance ID: 329826077
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder

Propiedades

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to brown
• solubility: DMSO: 2 mg/mL, clear (warmed)
• storage temp.: 2-8°C
• SMILES string: ClC1=CC(Cl)=C(N2C(C3=CC=C(Cl)C=C3)=C(C)C(C(N)=O)=N2)C=C1
• InChI key: BBUKVPCUOHFAQN-UHFFFAOYSA-N

Descripción

Biochem/physiol Actions

AM4113 is a Cannabinoid CB-1 neutral antagonist.

AM4113 is a Cannabinoid CB-1 neutral antagonist. AM4113 reduced reward and reinstatement of drug-seeking behavior, reducing cue-induced reinstatement in monkeys trained to self-administer cocaine.

AM4113 is a pyrazole-3-carboxamide analog of rimonabant (SR141716A). In rats, it suppresses food-motivated behaviors and food intake, thereby reducing weight gain without inducing nausea. AM4113 has poor oral bioavailability. Therefore, it may not act as an effective appetite suppressant in humans.

Información de seguridad

• Códigos de peligro: H413
• Indicaciones de precaución: P273 - P501
• Hazard Classifications: Aquatic Chronic 4
• Clase de almacenamiento: 11 - Combustible Solids
• ¿Qué está pasando?: WGK 3
• Punto de inflamación (°F): Not applicable
• Punto de inflamación (°C): Not applicable