SML0396

Tafenoquine succinate

≥95% (HPLC)

• Sinónimos: N-[2,6-Dimethoxy-4-methyl-5-[3-(trifluoromethyl)phenoxy]quinolin-8-yl]pentane-1,4-diamine, SB-252263, WR 238605
• Fórmula empírica (notación de Hill): C₂₄H₂₈F₃N₃O₃ · C₄H₆O₄
• Número de CAS: 106635-81-8
• Peso molecular: 581.58
• Número MDL: MFCD00892249
• Código UNSPSC: 12352200
• ID de la sustancia en PubChem: 329825392
• NACRES: NA.77

Propiedades

• Ensayo: ≥95% (HPLC)
• Formulario: powder
• condiciones de almacenamiento: desiccated
• color: white to beige
• solubilidad: DMSO: 5 mg/mL (clear solution)
• temp. de almacenamiento: 2-8°C
• cadena SMILES: OC(=O)CCC(O)=O.COc1cc(C)c2c(Oc3cccc(c3)C(F)(F)F)c(OC)cc(NC(C)CCCN)c2n1
• InChI: 1S/C24H28F3N3O3.C4H6O4/c1-14-11-20(32-4)30-22-18(29-15(2)7-6-10-28)13-19(31-3)23(21(14)22)33-17-9-5-8-16(12-17)24(25,26)27;5-3(6)1-2-4(7)8/h5,8-9,11-13,15,29H,6-7,10,28H2,1-4H3;1-2H2,(H,5,6)(H,7,8)
• Clave InChI: CQBKFGJRAOXYIP-UHFFFAOYSA-N

Descripción

Acciones bioquímicas o fisiológicas

Tafenoquine has been generally generated for oral administration and drug absorption increases when taken along with food.[1] It is known to possess a longer half life.[2]

Tafenoquine is an antimalarial primaquine analog being investigated to treat and prevent Plasmodium vivax infections. It can eliminate both blood and liver stages of Plasmodium vivax. Tafenoquine has also been tested as a therapy for leishmaniasis.

Tafenoquine is an antimalarial.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable