T3955

TNP

≥95% (HPLC)

• Sinónimos: N2-(m-Trifluorobenzyl), N6-(p-nitrobenzyl)purine; N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-9H-Purine-2,6-diamine; N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-1H-Purine-2,6-diamine
• Fórmula empírica (notación de Hill): C₂₀H₁₆F₃N₇O₂
• Número de CAS: 519178-28-0
• Peso molecular: 443.38
• Número MDL: MFCD16875436
• Código UNSPSC: 12352200
• ID de la sustancia en PubChem: 329826781
• NACRES: NA.77

Propiedades

• Nivel de calidad: 100
• Análisis: ≥95% (HPLC)
• formulario: powder
• condiciones de almacenamiento: protect from light
• color: yellow
• solubilidad: DMSO: ≥10 mg/mL
• emisor: Novartis
• temp. de almacenamiento: 2-8°C
• cadena SMILES: [O-][N+](=O)c1ccc(CNc2nc(NCc3cccc(c3)C(F)(F)F)nc4[nH]cnc24)cc1
• InChI: 1S/C20H16F3N7O2/c21-20(22,23)14-3-1-2-13(8-14)10-25-19-28-17(16-18(29-19)27-11-26-16)24-9-12-4-6-15(7-5-12)30(31)32/h1-8,11H,9-10H2,(H3,24,25,26,27,28,29)
• Clave InChI: DDSBPUYZPWNNGH-UHFFFAOYSA-N

Descripción

Acciones bioquímicas o fisiológicas

TNP is a potent and selective IP6K inhibitor; less selective inhibitor of IP3K. Discovery of TNP as an inositol trisphosphate (IP3) kinase inhibitor was first reported in 2002, However, a recent reference shows that TNP is more potent as an IP6K inhibitor, making it valuable for study of inositol pyrophosphates.

Características y beneficios

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Nota de preparación

TNP is soluble in DMSO at a concentration that is greater than or equal to 10 mg/ml.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable