The Positive Control functions as a system control to verify the functionality of the kit components. The resulting OD will not be utilized in any calculations. Any signal within the standard curve range that demonstrates competition in the assay indicates that the assay is performing as anticipated.
RAB0010
Angiotensin II EIA Kit
for serum, plasma, culture supernatant and cell lysates
Sinónimos:
Angiotensinogen, Serpin A8
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1 KIT
577,00 €
577,00 €
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1 KIT
577,00 €
About This Item
Código UNSPSC:
12352204
NACRES:
NA.32
577,00 €
Póngase en contacto con nuestro Servicio de Atención al Cliente para disponibilidad
Productos recomendados
reactividad de especies
mouse, human, rat
envase
kit of 96 wells (12 strips x 8 wells)
técnicas
ELISA: suitable
enzyme immunoassay: suitable
entrada
sample type cell lysate
sample type culture supernatant(s)
sample type serum
sample type plasma
assay range
inter-assay cv: <15%
intra-assay cv: <10%
sensitivity: 2.62 pg/mL
standard curve range: 0.1-1000 ng/mL
método de detección
colorimetric
Condiciones de envío
wet ice
temp. de almacenamiento
−20°C
Información sobre el gen
human ... AGT(183)
Categorías relacionadas
Descripción general
The Angiotensin II Enzyme Immunoassay (EIA) Kit is an in vitro quantitative assay for detecting Angiotensin II peptide based on the principle of Competitive Enzyme Immunoassay. EIA-ANGII-1 can theoretically detect all active angiotensins, including ANGI, ANGII, ANGIII and ANGIV. However, it does not detect inactive angiotensinogen.
Inmunógeno
Angiotensin II, synthetic peptide
Aplicación
For research use only. Not for use in diagnostic procedures.
Angiotensin II EIA Kit has been used for analyzing circulating and serum levels of angiotensin II (Ang II) in mice and rats respectively.[3][1]
Angiotensin II EIA Kit has been used for analyzing circulating and serum levels of angiotensin II (Ang II) in mice and rats respectively.[3][1]
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Acciones bioquímicas o fisiológicas
Study on in vitro model shows that mechanical stretch induced Ang II release plays a vital role in mediating stretch-induced hypertrophic response.[4] Ang II is implicated in maintaining blood pressure and has an important role in hypertension and in the pathophysiology of cardiovascular disorders. Ang II also has an essential role in growth induction, cell migration and mitosis of vascular smooth muscle cells. It enhances the production of collagen type I and III in fibroblasts, that results in thickening of the vascular wall and myocardium, and fibrosis. Variation in Ang II gene increases the risk of myocardial infarction, hypertension and left ventricular hypertrophy.[5] Ang II expression is associated with heart failure, cardiac remodeling, diabetes, and the proliferative and inflammatory responses to arterial injury. The pharmacological agents such as angiotensin II-converting enzyme inhibitors or angiotensin II receptor antagonists can be used for treating Ang II-induced hypertension and congestive heart failure.[6]
Los componentes del kit también están disponibles por separado
Referencia del producto
Descripción
SDS
- RABHRP3HRP-StreptavidinSDS
Palabra de señalización
Warning
Frases de peligro
Consejos de prudencia
Clasificaciones de peligro
Met. Corr. 1
Código de clase de almacenamiento
8A - Combustible corrosive hazardous materials
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