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L9507

Lactoferrin from bovine milk

≥85% (SDS-PAGE)

Sinónimos:

Bos d LF, Lactotransferrin

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Talla/SKUDisponibilidadPrecio
10 mg
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116,00 €
50 mg
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407,00 €

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Número CAS:
936541-36-5
UNSPSC Code:
12352202
NACRES:
NA.61
MDL number:
MFCD00131481
Form:
powder
Assay:
≥85% (SDS-PAGE)
Biological source:
bovine milk
Mol wt:
~87 kDa

116,00 €

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biological source

bovine milk

Quality Segment

assay

≥85% (SDS-PAGE)

form

powder

mol wt

~87 kDa

technique(s)

fractionation: suitable

solubility

H2O: soluble 10 mg/mL

UniProt accession no.

storage temp.

2-8°C

Gene Information

cow ... LTF(280846)

Application

Lactoferrin was used in the fractionation of lactoperoxidase and lactoferrin from bovine whey using a cation exchange membrane. It was used in the determination of lactoferrin and immunoglobulin G in animal milks by new immunosensors.

Biochem/physiol Actions

Lactoferrin is an iron binding protein. It is structurally similar to transferrin, the plasma iron transport protein; but lactoferrin has a much higher affinity for iron (250 fold). It is very abundant in colostrum and small amounts can also be found in tears, saliva, mucous secretions and in the secondary granules of neutrophils. It is made by mucosal epithelium and neutrophils and is released by these cells in response to inflammatory stimuli. Bacterial growth is inhibited by its ability to sequester iron and also permeabilize bacterial cell walls by binding to lipopolysaccharides through its N-terminus. Lactoferrin can inhibit viral infection by binding tightly to the viral envelope protein. This prevents cell-virus fusion by blocking the binding domain. Lactoferrin appears to activate host defense systems in part by stimulating the release of interleukin-8, a neutrophil activator. It may also be involved in antibody and interleukin synthesis, lymphocyte proliferation and complement activation.

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Este artículo
L3770L4040L6010
Lactoferrin from bovine milk ≥85% (SDS-PAGE)

Sigma-Aldrich

L9507

Lactoferrin from bovine milk

Lactoferrin from human milk Iron saturated, ≥85% (SDS-PAGE)

Sigma-Aldrich

L3770

Lactoferrin from human milk

Lactoferrin human recombinant, expressed in rice, Partially iron saturated, ≥90% (SDS-PAGE)

Sigma-Aldrich

L4040

Lactoferrin human

α-Lactalbumin from bovine milk Type III, calcium depleted, ≥85% (PAGE), lyophilized powder

Sigma-Aldrich

L6010

α-Lactalbumin from bovine milk

description

≥85% (SDS-PAGE)

description

Iron saturated, ≥85% (SDS-PAGE)

description

recombinant, expressed in rice, Partially iron saturated, ≥90% (SDS-PAGE)

description

Type III, calcium depleted, ≥85% (PAGE), lyophilized powder

technique(s)

fractionation: suitable

technique(s)

microbiological culture: suitable

technique(s)

microbiological culture: suitable

technique(s)

indirect ELISA: suitable

biological source

bovine milk

biological source

human milk

biological source

human

biological source

bovine milk

assay

≥85% (SDS-PAGE)

assay

≥85% (SDS-PAGE)

assay

≥90% (SDS-PAGE), ≥70% protein basis (Bradford)

assay

≥85% (PAGE)

form

powder

form

powder

form

powder

form

lyophilized powder

mol wt

~87 kDa

mol wt

82.4 kDa

mol wt

-

mol wt

14,178 Da by calculation

solubility

H2O: soluble 10 mg/mL

solubility

phosphate buffer: 10 mg/mL at 25 °C (0.01 M phosphate buffer, 0.0027 M potassium chloride and 0.137 M sodium chloride, pH 7.4)

solubility

H2O: soluble 10 mg/mL

solubility

H2O: soluble 10 mg/mL, clear to slightly hazy, colorless to faintly yellow

Clase de almacenamiento

11 - Combustible Solids

¿Qué está pasando?

WGK 3

Punto de inflamación (°F)

Not applicable

Punto de inflamación (°C)

Not applicable

EPI (equipos de protección individual)

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number

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Preguntas

  1. Is this product dissolvable in plant based oils?

    1 respuesta

    1. This product has not been tested for solubility in plant oils. However, it can be solubilized in water and aqueous solutions, 10 mg/mL of water and 1 mg/mL of PBS, respectively. A brief search of the literature shows that oil emulsions have been frequently studied.

      See the link below for a publication that may be helpful.
      https://pubs.acs.org/doi/full/10.1021/jf9809939

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