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Merck

L8045

Sigma-Aldrich

Liquiritin

from Glycyrrhizae root (licorice root), ≥98% (HPLC)

Sinónimos:

4′,7-Dihydroxyflavanone 4′-glucoside, Liquiritoside

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179,00 €
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179,00 €


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10 MG
179,00 €
50 MG
700,00 €

About This Item

Fórmula empírica (notación de Hill):
C21H22O9
Número de CAS:
Peso molecular:
418.39
Número MDL:
Código UNSPSC:
12352200
NACRES:
NA.25

179,00 €


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origen biológico

Glycyrrhizae root (licorice root)

Nivel de calidad

Ensayo

≥98% (HPLC)

Formulario

powder

aplicaciones

metabolomics
vitamins, nutraceuticals, and natural products

temp. de almacenamiento

2-8°C

cadena SMILES

O=C1C2=CC=C(O)C=C2O[C@H](C3=CC=C(O[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O4)C=C3)C1

InChI

1S/C21H22O9/c22-9-17-18(25)19(26)20(27)21(30-17)28-12-4-1-10(2-5-12)15-8-14(24)13-6-3-11(23)7-16(13)29-15/h1-7,15,17-23,25-27H,8-9H2/t15-,17+,18+,19-,20+,21+/m0/s1

Clave InChI

DEMKZLAVQYISIA-ZRWXNEIDSA-N

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Descripción general

Liquiritin is a type of flavone, present as an active ingredient in Glycyrrhiza uralensis and Glycyrrhiza glabra extract. It is a constituent of many traditional Chinese medicine formulas popularly used as a cure for asthma, peptic ulcers, and cough.[1][2][3]

Aplicación

Liquiritin has been used to analyze the extract of Glycyrrhiza uralensis and examine its components for anti-Hepatitis C virus activity.[1]

Acciones bioquímicas o fisiológicas

Liquiritin has been attributed to show antidepressant-like and antioxidant activity.[4] It causes apoptosis in cell lines having gastric cancer and promyelocytic leukemia. Liquiritin also demonstrates neurotrophic effects and hence has been considered as a potential contender for the management of different neurodegenerative diseases.[2] It shows an anti-inflammatory property with protection to the liver against oxidative damage.[3] It has depigmenting ability and is a potential medicine for melasma.[5]

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


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Zhiyu Zhao et al.
Behavioural brain research, 194(1), 108-113 (2008-07-29)
Many flavonoids extracted from nature plants have been reported to exert antidepressant-like effect in animal studies. The present study was designed to observe the effects of liquiritin, a flavone compound derived from Glycyrrhiza uralensis, on the behaviors of chronic variable
Zheng-Ai Chen et al.
Cytotechnology, 60(1-3), 125-132 (2009-10-01)
Neurite outgrowth and neuronal differentiation play a crucial role in the development of the nervous system. Understanding of neurotrophins induced neurite outgrowth was important to develop therapeutic strategy for axon regeneration in neurodegenerative diseases as well as after various nerve
Qiuyan Guo et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 123, 109812-109812 (2020-01-17)
Wu-tou decoction (WTD), a classic Traditional Chinese medicine formula, has been extensively used in the treatment of neuropathic pain (NP) such as chronic inflammatory pain, trigeminal neuralgia, and cancer-induced pain. Our previous studies have shown that the severity of mechanical
M Amer et al.
International journal of dermatology, 39(4), 299-301 (2000-05-16)
Twenty women with a clinical diagnosis of melasma were treated with liquiritin cream on one side of the face and with a vehicle cream on the other side twice daily for 4 weeks. Patients were advised to avoid sun exposure
Ji-Yeon Yu et al.
Molecules (Basel, Switzerland), 20(7), 13041-13054 (2015-07-25)
This study provides the scientific basis for the anti-inflammatory effects of licorice extract in a t-BHP (tert-butyl hydrogen peroxide)-induced liver damage model and the effects of its ingredients, glycyrrhizic acid (GA), liquiritin (LQ) and liquiritigenin (LG), in a lipopolysaccharide (LPS)-stimulated

Preguntas

  1. Which genus of licorice root is the Liquiritin from; G.glabra, G.inflata, or G.uralensis?

    1 respuesta
    1. Regrettably, this information is not specified in the available documentation. Please be directed to the Certificate of Origin for Product L8045 and the lot in possession for all the relevant origin information. Lot MKBV8555V may be used as an example.

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