A8011
Antifoam C Emulsion
aqueous-silicone emulsion
Sinónimos:
Antifoaming Agent Emulsion
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About This Item
Código UNSPSC:
12161900
NACRES:
NA.25
Productos recomendados
origen biológico
synthetic
Nivel de calidad
Formulario
emulsion
contiene
emulsifier
técnicas
cell culture | hybridoma: suitable
microbiological culture: suitable
mp
0 °C (32 °F)
Categorías relacionadas
Descripción general
Antifoam C emulsion is an aqueous emulsion containing 30% active silicone. This silicone-based antifoam emulsion consists of non-ionic emulsifiers different from those in antifoam emulsions B and Y-30. Antifoam C emulsion can be prediluted with 3-10 parts of cool water to aid in dispersion. Prediluted suspensions should be used immediately. Antifoam C emulsion is typically effective at 1-10 ppm. The flow properties of antifoam C emulsion are such that it can be pumped on an as-needed basis to a fermenter system with sufficient agitation to disperse the antifoam. Antifoam C emulsion can be used to regulate headspace foaming in mammalian cell culture bioreactors up to 30 ppm concentration.
Aplicación
Antifoam C emulsion has been used:
- as a supplement in RO-H2O and a chemically defined culture medium to determine volumetric mass transfer coefficient (kLa) of mammalian cell culture
- as a component of feed medium,
- as a steam-sterilized antifoaming agent in a biocontroller for pH-stat fed-batch cultivations
- as a supplement in fed batch medium to mimic the typical large-scale cultivation conditions
Características y beneficios
- Minimizes compatibility issues with biological systems
- Highly effective defoamer at low concentrations
- Highly effective and versatile silicone defoamer
Otras notas
A 30% aqueous emulsion of polydimethylsiloxane concentrate.
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Palabra de señalización
Warning
Frases de peligro
Consejos de prudencia
Clasificaciones de peligro
Eye Irrit. 2 - STOT SE 3
Órganos de actuación
Respiratory system
Código de clase de almacenamiento
10 - Combustible liquids
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Equipo de protección personal
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
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In aerobic cell cultivation processes, dissolved oxygen is a key process parameter, and an optimal oxygen supply has to be ensured for proper process performance. To achieve optimal growth and/or product formation, the rate of oxygen transfer has to be
Characterizing the Effects of Antifoam C Emulsion on Oxygen Mass Transfer within the BIOne Drilled-Hole Sparger and Microsparger Single-Use Bioreactor Systems
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Journal of biotechnology, 150(2), 224-231 (2010-08-28)
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