L6785
Lactacystin
≥90% (HPLC), powder, proteosome inhibitor
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| Talla/SKU | Disponibilidad | Precio |
|---|---|---|
0.2 mg | Póngase en contacto con nuestro Servicio de Atención al Cliente para disponibilidad | 401,00 € |
Acerca de este artículo
401,00 €
Nombre del producto
Lactacystin, ≥90% (HPLC)
Quality Segment
assay
≥90% (HPLC)
form
powder
potency
4 nM Ki (proteasome inhibitor)
solubility
water: 10 mg/mL, clear, colorless
storage temp.
−20°C
SMILES string
CC(C)[C@H](O)[C@]1(NC(=O)[C@H](C)[C@@H]1O)C(=O)SC[C@H](NC(C)=O)C(O)=O
InChI
1S/C15H24N2O7S/c1-6(2)10(19)15(11(20)7(3)12(21)17-15)14(24)25-5-9(13(22)23)16-8(4)18/h6-7,9-11,19-20H,5H2,1-4H3,(H,16,18)(H,17,21)(H,22,23)/t7-,9+,10+,11+,15-/m1/s1
InChI key
DAQAKHDKYAWHCG-RWTHQLGUSA-N
General description
Application
- as a proteasome inhibitor to inhibit protein degradation
- to inhibit proteasomal activity of cells for live cell imaging
- to block proteasomal proteolysis in human monocyte-derived dendritic cells (MoDCs) for 24 h
- to provide unilateral injection to animals to induce nigrostriatal lesions
Biochem/physiol Actions
1 of 1
Este artículo | |||
|---|---|---|---|
| description ≥90% (HPLC) | description Lactacystin, Synthetic, CAS 1258004-00-0, is an irreversible inhibitor of 20S proteasome inhibitor (IC50 = 500 nM). A covalent inhibitor of the chymotrypsin & trypsin-like activities of proteasome. | description ≥95% (HPLC), powder | description esterase inhibitor |
| assay ≥90% (HPLC) | assay ≥99% (HPLC) | assay ≥95% (HPLC) | assay ≥98% (HPLC) |
| form powder | form solid | form powder | form powder |
| Quality Level 200 | Quality Level 100 | Quality Level 200 | Quality Level 100 |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. 2-8°C |
| solubility water: 10 mg/mL, clear, colorless | solubility water: soluble, DMSO: 50 mg/mL | solubility DMSO: 7.5 mg/mL | solubility methanol: 10 mg/mL, clear, colorless |
| potency 4 nM Ki (proteasome inhibitor) | potency - | potency - | potency - |
Clase de almacenamiento
11 - Combustible Solids
¿Qué está pasando?
WGK 3
Punto de inflamación (°F)
Not applicable
Punto de inflamación (°C)
Not applicable
EPI (equipos de protección individual)
Eyeshields, Gloves, type N95 (US)
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