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Merck

H4131

Sigma-Aldrich

Hemoglobin porcine

lyophilized powder

Sinónimos:

Hb

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About This Item

Número de CAS:
Número MDL:
Código UNSPSC:
12352202
eCl@ss:
42030116
NACRES:
NA.61

origen biológico

Porcine

formulario

lyophilized powder

solubilidad

H2O: soluble 10 mg/mL

Nº de acceso UniProt

temp. de almacenamiento

2-8°C

Información sobre el gen

Descripción general

Hemoglobin is the major component of red blood cells, and is responsible for their red color. Its normal concentration in erythrocytes is 34%. Hemoglobin is the most important respiratory protein of vertebrates by virtue of its ability to transport oxygen from the lungs to body tissues, and to facilitate the return transport of carbon dioxide.

Aplicación

Hemoglobin from porcine was used to test the role of the L-arginine/nitric oxide pathway in relaxation of isolated human penile cavernous tissue and circumflex veins. It was also used to study the role of nitric oxide in neurogenic vasodilation of porcine cerebral artery.

Acciones bioquímicas o fisiológicas

The Fe2+/Fe3+ balance is a physiological indicator of blood oxygenation. Deoxygenated hemoglobin accessorizes a feedback loop by reducing nitrite to NO, a vasodilator which enhances blood flow to oxygen-deprived tissues.
Oxygen transporter, NO scavenger

Precaución

Since native hemoglobin is readily oxidized in air, these preparations may be predominantly methemoglobin.

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)


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F Y Chen et al.
The Journal of pharmacology and experimental therapeutics, 265(1), 339-345 (1993-04-01)
A superfusion bioassay cascade, with porcine pial arteries as donor tissues and rabbit aortic rings as detector tissues, was used to examine the role of nitric oxide (NO) in cerebral nonadrenergic, noncholinergic neurogenic vasodilation. All arteries were mechanically denuded of
H J Kirkeby et al.
Acta physiologica Scandinavica, 149(3), 385-392 (1993-11-01)
In human penile corpus cavernosum strips, pre-contracted by noradrenaline, electrical stimulation of nerves evoked non-adrenergic, non-cholinergic (NANC) relaxant responses which could be inhibited by tetrodotoxin 10(-6) M, NG-nitro-L-arginine (L-NNA) 10(-7)-10(-4) M, and oxyhaemoglobin 10(-5) M, but not by methylene blue
Sanna M Mäkelä et al.
British journal of clinical pharmacology, 87(12), 4625-4635 (2021-04-29)
Use of nonsteroidal anti-inflammatory drugs (NSAIDs) can cause damage to the gastric and duodenal mucosa. Some probiotics have proven useful in ameliorating the harmful side-effects of NSAIDs. Our aim was to evaluate whether oral administration of Bifidobacterium animalis ssp. lactis
Chung-Chieh Yu et al.
Optics express, 16(20), 16227-16239 (2008-10-01)
We report a fully quantitative spectroscopy imaging instrument for wide area detection of early cancer (dysplasia). This instrument provides quantitative maps of tissue biochemistry and morphology, making it a potentially powerful surveillance tool for objective early cancer detection. We describe
Xingyi Jiang et al.
Foods (Basel, Switzerland), 10(8) (2021-08-28)
Different types of enzyme-linked immunosorbent assays (ELISA) have been widely used to control food safety and quality. To develop an accurate and reproducible ELISA, false immunodetection results caused by non-specific binding (NSB) and cross-reaction must be prevented. During the case

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