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Merck

C9017

Sigma-Aldrich

Concanavalin A from Canavalia ensiformis (Jack bean)

Sepharose conjugate, buffered aqueous suspension

Sinónimos:

ConA

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About This Item

Código UNSPSC:
12161501
NACRES:
NA.32

origen biológico

Canavalia ensiformis

conjugado

Sepharose conjugate

formulario

buffered aqueous suspension

contiene

20% ethanol as preservative

Extensión del etiquetado

10-16 mg per mL

matriz

Sepharose 4B

activación de la matriz

cyanogen bromide

unión a la matriz

amino

espaciador de matriz

1 atom

capacidad

≥25 mg/mL binding capacity (thyroglobulin)

temp. de almacenamiento

2-8°C

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Aplicación

Used for the purification of glycoproteins containing mannose.

Acciones bioquímicas o fisiológicas

Con A is not blood group specific but has an affinity for terminal α-D-mannosyl and α-D-glucosyl residues. Ca2+ and Mn2+ ions are required for activity. Con A dissociates into dimers at pH 5.6 or below. Between pH 5.8 and pH 7.0, Con A exists as a tetramer; above pH 7.0 higher aggregates are formed. Con A exhibits mitogenic activity which is dependent on its degree of aggregation. Succinylation results in an active dimeric form which remains a dimer above pH 5.6.

Forma física

Suspension in 0.1 M acetate buffer, pH 6.0, containing 1 M NaCl, and 1 mM each of CaCl2 , MgCl2, and MnCl2

Nota de análisis

Where reported, agglutination activity is expressed in μg/ml and is determined from serial dilutions in phosphate buffered saline, pH 6.8, containing Ca2+ and Mn2+ of a 1 mg per mL solution. This activity is the lowest concentration to agglutinate a 2% suspension of human erythrocytes after 1 hr incubation at 25 °C.

Información legal

Sepharose is a trademark of Cytiva

Producto relacionado

Referencia del producto
Descripción
Precios

Pictogramas

Health hazard

Palabra de señalización

Danger

Frases de peligro

Clasificaciones de peligro

Repr. 2 - Resp. Sens. 1 - Skin Sens. 1

Código de clase de almacenamiento

3 - Flammable liquids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

102.2 °F

Punto de inflamabilidad (°C)

39 °C


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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