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L7647

Sigma-Aldrich

Concanavalin A from Canavalia ensiformis (Jack bean)

Type VI, lyophilized powder

Sinónimos:

Con A

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About This Item

Número de CAS:
11028-71-0
Número CE:
234-258-2
Número MDL:
MFCD00071069
Código UNSPSC:
12352202
NACRES:
NA.32

origen biológico

Canavalia ensiformis

tpo

Type VI

formulario

lyophilized powder

potencia

≤20 μg per mL agglutination activity

impurezas

Carbohydrate, essentially free
 salt, essentially free

solubilidad

water: 1 % (w/v)

temp. de almacenamiento

−20°C

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Aplicación

Concanavalin A from Canavalia ensiformis (Jack bean) has been used for developing zwitterion-immobilized molecularly imprinted polymers (ziMIPs) for protein crystallization. It has been also used in the preparation of protein loaded microgels to prevent enzymatic degradation of microgels for monitoring by confocal laser scanning microscope (CLSM).

Acciones bioquímicas o fisiológicas

Con A is not blood group specific but has an affinity for terminal α-D-mannosyl and α-D-glucosyl residues. Ca2+ and Mn2+ ions are required for activity. Con A dissociates into dimers at pH 5.6 or below. Between pH 5.8 and pH 7.0, Con A exists as a tetramer; above pH 7.0 higher aggregates are formed. Con A exhibits mitogenic activity which is dependent on its degree of aggregation. Succinylation results in an active dimeric form which remains a dimer above pH 5.6.

Nota de preparación

Highly purified by specific affinity chromatography.

Nota de análisis

Agglutination activity: Determined from serial dilutions of a 1 mg/mL solution (this activity is the lowest conc. to agglutinate a 2% suspension of human erythrocytes after 1 hr incubation at 25 °C). Requires Type A Human Blood.

Pictogramas

Health hazard
GHS08

Palabra de señalización

Danger

Frases de peligro

H317,H334,H361

Clasificaciones de peligro

Repr. 2 - Resp. Sens. 1 - Skin Sens. 1

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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