AC-0344

GRIA2 (EP387) Rabbit Monoclonal Primary Antibody

• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• forma del anticuerpo: Ig fraction of antiserum
• clon: monoclonal
• descripción: For In Vitro Diagnostic Use in Select Regions (See Chart)
• formulario: buffered aqueous solution
• técnicas: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:20
• Condiciones de envío: wet ice
• temp. de almacenamiento: 2-8°C
• visualización: (cytoplasm/membrane)

Descripción

Descripción general

Glutamate receptor 2 (GRIA2) is a ligand-gated ion channel that uses L-glutamate for excitatory synaptic transmission expressed in the central nervous system. A recent gene expression profiling study reported >100 fold GRIA2 induction in solitary fibrous tumors compared with control tissues. Immunohistochemistry studies demonstrated GRIA2 positivity in the majority of solitary fibrous tumors (64-86%). Its diagnostic performance yields 64% sensitivity, 92% specificity, with 41% and 97% positive and negative predictive value, respectively for the differential diagnosis of solitary fibrous tumors versus other mesenchymal soft tissue tumors. GRIA2 may be a useful marker to identify STAT6-negative solitary fibrous tumors.

Calidad

IVD

IVD

IVD

RUO

Forma física

Solution in Tris Buffer, pH 7.3-7.7, with 1%BSA and &< 0.1% Sodium Azide

Otras notas

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Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable