85555

Spectinomycin dihydrochloride pentahydrate

≥98.0% (AT)

• Fórmula empírica (notación de Hill): C₁₄H₂₄N₂O₇ · 2HCl · 5H₂O
• Número de CAS: 22189-32-8
• Peso molecular: 495.35
• Beilstein: 5684150
• Número CE: 244-554-3
• Número MDL: MFCD00150886
• Código UNSPSC: 51101500
• ID de la sustancia en PubChem: 57653052

Propiedades

• origen biológico: synthetic
• Ensayo: ≥98.0% (AT)
• Formulario: solid
• color: white
• solubilidad: H₂O: 50 mg/mL, clear, faintly yellow
• espectro de actividad antibiótica: Gram-negative bacteria; Gram-positive bacteria
• Modo de acción: protein synthesis | interferes
• temp. de almacenamiento: 2-8°C
• cadena SMILES: Cl[H].Cl[H].[H]O[H].[H]O[H].[H]O[H].[H]O[H].[H]O[H].[H][C@@]12O[C@H](C)CC(=O)[C@]1(O)O[C@]3([H])[C@@H](NC)[C@@H](O)[C@@H](NC)[C@H](O)[C@@]3([H])O2
• InChI: 1S/C14H24N2O7.2ClH.5H2O/c1-5-4-6(17)14(20)13(21-5)22-12-10(19)7(15-2)9(18)8(16-3)11(12)23-14;;;;;;;/h5,7-13,15-16,18-20H,4H2,1-3H3;2*1H;5*1H2/t5-,7-,8+,9+,10+,11-,12-,13+,14+;;;;;;;/m1......./s1
• Clave InChI: DCHJOVNPPSBWHK-UXXUFHFZSA-N

Descripción

Descripción general

Chemical structure: aminoglycoside

Aplicación

Spectinomycin is an aminocyclitol antibiotic derived from Streptomyces spectabilis. It has been shown to have a wide variety of uses, including treating acute gonorrheal urethritis and cervictis, to mark cell layers to monitor cell fate during leaf development, as a selection marker in plant related transformation systems for plant cells containing the marker gene Spcr, to study respiratory tract infections of cattle caused by Pasteurella multocida and Mannheimia haemolytica, and to generate plants deficient for the plastid-encoded RNA polymerase on MS-agar media. Spectinomycin also has use in amplification of low copy number plasmid carrying replicons. It is recommended for use in cell culture applications at 7.5-20 mg/L.

Precaución

Solutions can be stored at 2-8°C for several weeks or at -20°C for more extended periods.

Nota de preparación

Stock solutions should be prepared at 10 mg/mL in water and filter sterilized.

Otras notas

Keep container tightly closed in a dry and well-ventilated place. Store under inert gas.

Información de seguridad

• Pictogramas: GHS07
• Palabra de señalización: Warning
• Frases de peligro: H315,H319,H335
• Consejos de prudencia: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Clasificaciones de peligro: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Órganos de actuación: Respiratory system
• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)