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P2698000

Prednicarbate

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

(11β)-17-[(Ethoxycarbonyl)oxy]-11-hydroxy-21-(1-oxopropoxy)pregna-1,4-diene-3,20-dione

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110 MG
149,00 €

149,00 €

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110 MG
149,00 €

About This Item

Fórmula empírica (notación de Hill):
C27H36O8
Número de CAS:
73771-04-7
Peso molecular:
488.57
Número CE:
277-590-3
Código UNSPSC:
41116107
NACRES:
NA.24

149,00 €

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grado

pharmaceutical primary standard

familia API

prednicarbate

fabricante / nombre comercial

EDQM

aplicaciones

pharmaceutical (small molecule)

Formato

neat

cadena SMILES

O(C1(C2(C(C3C(C4(C(=CC(=O)C=C4)CC3)C)C(C2)O)CC1)C)C(=O)COC(=O)CC)C(=O)OCC

InChI

1S/C27H36O8/c1-5-22(31)34-15-21(30)27(35-24(32)33-6-2)12-10-19-18-8-7-16-13-17(28)9-11-25(16,3)23(18)20(29)14-26(19,27)4/h9,11,13,18-20,23,29H,5-8,10,12,14-15H2,1-4H3

Clave InChI

FNPXMHRZILFCKX-UHFFFAOYSA-N

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Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

Prednicarbate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Envase

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Otras notas

Sales restrictions may apply.

Producto relacionado

Referencia del producto
Descripción
Precios

Y0001630

Prednicarbate for system suitability A, European Pharmacopoeia (EP) Reference Standard

1554909

Prednicarbate, United States Pharmacopeia (USP) Reference Standard

1554910

Prednicarbate Related Compound A, United States Pharmacopeia (USP) Reference Standard

1554931

Prednicarbate Related Compound C, United States Pharmacopeia (USP) Reference Standard

1554920

Prednicarbate Related Compound B, United States Pharmacopeia (USP) Reference Standard

Y0002231

Prednicarbate for peak identification, CRS, European Pharmacopoeia (EP) Reference Standard

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Prednicarbate, pharmaceutical secondary standard, certified reference material

PHR3102

Prednicarbate Related Compound C, pharmaceutical secondary standard, certified reference material

Pictogramas

Health hazard
GHS08

Palabra de señalización

Danger

Frases de peligro

H360D

Consejos de prudencia

P201 - P280 - P308 + P313

Clasificaciones de peligro

Repr. 1B

Código de clase de almacenamiento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number

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Aditya K Gupta et al.
Journal of cutaneous medicine and surgery, 8(4), 244-247 (2005-08-11)
Topical steroids have been a popular choice for treating various cutaneous disorders; however, the potential for significant local and systemic adverse events, like skin atrophy and hypothalamic-pituitary-adrenal (HPA) axis suppression, has limited their use. This article reviews the topical steroid
I Spika et al.
Skin pharmacology and applied skin physiology, 16(3), 143-150 (2003-04-05)
As compared to standard glucocorticoids (GC), prednicarbate (PC) is favorable in the treatment of eczema due to its high benefit/risk ratio. The remarkable anti-inflammatory effects of PC are in strong contrast to its reported low glucocorticoid receptor (GR) binding affinity.
Aditya K Gupta et al.
Journal of drugs in dermatology : JDD, 3(5), 553-556 (2004-11-24)
Prednicarbate is a non-halogenated, double-ester derivative of prednisolone that has become of interest for the treatment of inflammatory skin diseases, for example atopic dermatitis. In the past, topical steroids have been a popular choice for treating these diseases; however, the
Kerstin Katzer et al.
European journal of dermatology : EJD, 20(1), 82-84 (2009-10-03)
The epidermal growth factor receptor (EGFR) inhibitor cetuximab is used to treat advanced stages of solid tumors. Acneiform skin eruptions, the most common side effects of cetuximab, stigmatize the patient in daily life and may lower compliance. As oral treatment
A K Gupta et al.
Skin therapy letter, 9(10), 5-6 (2005-01-20)
Prednicarbate is a nonhalogenated corticosteroid that is used in the treatment of inflammatory skin diseases, for example atopic dermatitis. It has a favorable benefit-risk ratio, with an inflammatory action similar to that of a medium potency corticosteroid, but with a
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