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Merck

44577

Sigma-Aldrich

Doxiciclina hyclate

≥98.0% (TLC)

Sinónimos:

Clorhidrato de doxiciclina hemietalonato hemihidratado

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About This Item

Fórmula empírica (notación de Hill):
C22H24N2O8 · HCl · 0.5H2O · 0.5C2H6O
Número de CAS:
Peso molecular:
512.94
Beilstein:
5702728
Número MDL:
Código UNSPSC:
51101500
ID de la sustancia en PubChem:

origen biológico

synthetic

Ensayo

≥98.0% (TLC)

Formulario

powder

impurezas

≤5% water
≤7% ethanol

color

faintly yellow to yellow

solubilidad

H2O: 50 mg/mL, clear, yellow-green

espectro de actividad antibiótica

Gram-negative bacteria
Gram-positive bacteria
mycoplasma
parasites

Modo de acción

protein synthesis | interferes

cadena SMILES

Cl[H].Cl[H].[H]O[H].CCO.C[C@@H]1C2[C@H](O)C3[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]3(O)C(O)=C2C(=O)c4c(O)cccc14.C[C@@H]5C6[C@H](O)C7[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]7(O)C(O)=C6C(=O)c8c(O)cccc58

InChI

1S/2C22H24N2O8.C2H6O.2ClH.H2O/c2*1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29;1-2-3;;;/h2*4-7,10,14-15,17,25,27-29,32H,1-3H3,(H2,23,31);3H,2H2,1H3;2*1H;1H2/t2*7-,10?,14?,15-,17-,22-;;;;/m00..../s1

Clave InChI

HALQELOKLVRWRI-ZVACAFRPSA-N

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Descripción general

Chemical structure: tetracycline

Acciones bioquímicas o fisiológicas

Modo de acción: El hiclato de doxicilina inhibe la respuesta inflamatoria a la enfermedad de Lyme, causada por la espiroqueta Borrelia burgdorferi

. Espectro de actividad: Eficaz contra un inhibidor de amplio espectro de las metaloproteinasas de la matriz in vivo.

Otras notas

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.
This product has been replaced by D9891-SIGMA | Doxycycline hyclate ≥98% (TLC)

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Certificados de análisis (COA)

Lot/Batch Number

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How do I find price and availability?

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  4. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  5. Is doxycycline hyclate soluble in DMSO?

    According to literature sources, doxycycline hyclate is soluble in DMSO at a concentration of 100 mM.

  6. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

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