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Documentos

33973

Supelco

Clorsulon

VETRANAL®, analytical standard

Sinónimos:

4-Amino-6-(trichlorovinyl)-1,3-benzenedisulfonamide

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About This Item

Fórmula empírica (notación de Hill):
C8H8Cl3N3O4S2
Número de CAS:
60200-06-8
Peso molecular:
380.66
Número CE:
262-100-2
Número MDL:
MFCD00072006
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
329754714
NACRES:
NA.24

grado

analytical standard

Nivel de calidad

100

Línea del producto

VETRANAL®

caducidad

limited shelf life, expiry date on the label

técnicas

HPLC: suitable
gas chromatography (GC): suitable

aplicaciones

forensics and toxicology
pharmaceutical (small molecule)

formato

neat

cadena SMILES

Nc1cc(\C(Cl)=C(\Cl)Cl)c(cc1S(N)(=O)=O)S(N)(=O)=O

InChI

1S/C8H8Cl3N3O4S2/c9-7(8(10)11)3-1-4(12)6(20(14,17)18)2-5(3)19(13,15)16/h1-2H,12H2,(H2,13,15,16)(H2,14,17,18)

Clave InChI

QOVTVIYTBRHADL-UHFFFAOYSA-N

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Descripción general

Clorsulon, is a benzene sulphonamide and a flukicide, which is found to be effective against the adult and immature form of liver fluke, Fasciola hepatica in cattle.

Aplicación

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Productos recomendados

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Información legal

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
BCCG8206
BCBV4517
SZBE090XV
SZBB102XV
SZE9140X

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Y Vera Montenegro et al.
Parasitology research, 91(1), 1-4 (2003-07-05)
The efficacy of 5-chloro-2-methylthio-6-(1-napthyloxy)-1H-benzimidazole was evaluated with three commercial fasciolicides in terms of the percentage of egg reduction in cattle. Fifty Swiss cows were selected for inclusion in the trial based on finding eggs of Fasciola hepatica in their feces.
S F Sundlof et al.
Journal of veterinary pharmacology and therapeutics, 15(3), 282-291 (1992-09-01)
Clorsulon was measured in plasma and urine of sheep and goats after administration of a single intravenous (i.v.) and after a single oral dose of 7 mg/kg. A three-compartment model with elimination occurring from the central compartment was determined to
Induction of reversible urothelial cell hyperplasia in rats by clorsulon, a flukicide with weak carbonic anhydrase inhibitory activity
Lankas.RG and Peter.PC
Food And Chemical Toxicology, 30, 297-306 (1992)
M Meaney et al.
Parasitology research, 95(3), 201-212 (2005-01-13)
Three experiments have been carried out in vitro to determine the effect of oral and trans-tegumental uptake of clorsulon on the fine structure of the tegument and gut of Fasciola hepatica. Changes were assessed by transmission electron microscopy. In the
M Meaney et al.
Parasitology research, 92(3), 232-241 (2004-01-10)
Using transmission electron microscopy (TEM), both the tegument and gut of Fasciola hepatica were examined in an effort to identify and characterise the ultrastructural changes induced following treatment with the flukicidal drug clorsulon. Male Sprague-Dawley rats infected with F. hepatica
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