235989

Brij^® L4

average M_n ~362

• Sinónimos: Polyethylene glycol dodecyl ether, Polyoxyethylene (4) lauryl ether
• Fórmula lineal: (C₂₀H₄₂O₅)_n
• Número de CAS: 9002-92-0
• Número MDL: MFCD00043063
• Código UNSPSC: 12161900
• ID de la sustancia en PubChem: 24854130
• NACRES: NA.21

Propiedades

• descripción: non-ionic
• Nivel de calidad: 200
• mol peso: average M_n ~362
• índice de refracción: n20/D 1.451 (lit.)
• densidad: 0.95 g/mL at 25 °C (lit.)
• HLB: 9
• cadena SMILES: CCCCCCCCCCCCOCCOCCOCCOCCO
• InChI: 1S/C20H42O5/c1-2-3-4-5-6-7-8-9-10-11-13-22-15-17-24-19-20-25-18-16-23-14-12-21/h21H,2-20H2,1H3
• Clave InChI: WPMWEFXCIYCJSA-UHFFFAOYSA-N

Descripción

Descripción general

Brij^® L4 is a non-ionic surfactant. It comprises an alkyl (C12) tail attached to an oxyethylene headgroup.

Aplicación

Brij^® L4 has been used:

• as a surfactant for the synthesis of copper(I) oxide (Cu₂O) spherical nanoparticles using a microemulsion technique
• as a non-ionic surfactant for preparing reverse micelles to synthesize Pt₃Co alloy nanoparticles
• as a surfactant to enhance the efficiency of interfacial coupling of hydrophobic materials and to make hydrogel

Acciones bioquímicas o fisiológicas

Brij^® L4 exhibits amphiphilic properties. Brij L4 contains hydrophobic and hydrophilic regions that can form micelles and disperse hydrophobic drugs into the core of micelles. This in turn enhances drug solubility. Brij L4 also elicits a strong inhibitory effect against breast cancer resistance protein (BCRP) mediated drug efflux. It inhibits Taq adsorption better when compared to other commonly used surfactants. Brij L4 supports droplet polymerase chain reaction (PCR) in picoliter reaction volumes at standard Taq concentrations.

Información legal

Brij is a registered trademark of Croda International PLC

Información de seguridad

• Pictogramas: GHS07,GHS09
• Palabra de señalización: Warning
• Frases de peligro: H302,H315,H319,H411
• Consejos de prudencia: P264 - P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Clasificaciones de peligro: Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2
• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: dust mask type N95 (US), Eyeshields, Gloves