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Merck

03951

Sigma-Aldrich

N-Ethylformamide

≥99.0% (GC)

Sinónimos:

N-Formylethylamine

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About This Item

Fórmula lineal:
HCONHC2H5
Número de CAS:
Peso molecular:
73.09
Beilstein:
1737860
Número CE:
Número MDL:
Código UNSPSC:
12352100
ID de la sustancia en PubChem:
NACRES:
NA.22

Nivel de calidad

100
500

Análisis

≥99.0% (GC)

formulario

liquid

índice de refracción

n20/D 1.432

bp

202-204 °C

densidad

0.950 g/mL at 20 °C (lit.)

cadena SMILES

CCNC=O

InChI

1S/C3H7NO/c1-2-4-3-5/h3H,2H2,1H3,(H,4,5)

Clave InChI

KERBAAIBDHEFDD-UHFFFAOYSA-N

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Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

235.4 °F - closed cup

Punto de inflamabilidad (°C)

113 °C - closed cup

Equipo de protección personal

Eyeshields, Gloves


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H Cross et al.
Chemical research in toxicology, 3(4), 357-362 (1990-07-01)
Hepatotoxic formamides such as N-methylformamide (NMF) and N,N-dimethylformamide (DMF) are metabolized in vivo to N-acetyl-S-(N-methylcarbamoyl)cysteine via oxidation at the formyl carbon, which yields a reactive intermediate. The hypothesis was tested that this biotransformation route can be studied in vitro with
M R Del Carratore et al.
Environmental and molecular mutagenesis, 36(2), 97-104 (2000-10-03)
A cDNA coding for rat cytochrome P450 2E1 was cloned into the multicopy vector pYeDP60 and expressed in haploid RSY6 and diploid RS112 yeast strains of Saccharomyces cerevisiae under control of the GAL10-CYC1 promoter. Spectral and catalytic properties of the
P Kestell et al.
The Journal of pharmacology and experimental therapeutics, 240(1), 265-270 (1987-01-01)
The hepatotoxicity and metabolism of the following close analogs of the hepatotoxic antitumor agent N-methylformamide (NMF) were investigated in CBA/CA mice: N-ethylformamide (NEF), dimethylformamide (DMF), formamide and N-methylacetamide (NMA). Apart from NMF only NEF was potently hepatotoxic as measured by
S P Langdon et al.
Toxicology, 43(3), 239-249 (1987-03-01)
The induction of terminal differentiation in tumour cells represents a possible therapeutic strategy for treating cancer. The alkylformamides are 1 group of experimental compounds which have been shown to induce terminal differentiation in human HL-60 leukemia and murine Friend erythroleukemia
Gil-Soo Han et al.
The Journal of biological chemistry, 283(29), 20443-20453 (2008-05-07)
The Saccharomyces cerevisiae DGK1 gene encodes a diacylglycerol kinase enzyme that catalyzes the formation of phosphatidate from diacylglycerol. Unlike the diacylglycerol kinases from bacteria, plants, and animals, the yeast enzyme utilizes CTP, instead of ATP, as the phosphate donor in

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