ABT148

Anti-Claudin-11 Antibody

from rabbit, purified by affinity chromatography

• Sinónimos: Claudin-11, Oligodendrocyte-specific protein
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• purificado por: affinity chromatography
• reactividad de especies: human
• reactividad de especies (predicha por homología): chimpanzee (based on 100% sequence homology)
• técnicas: western blot: suitable
• Nº de acceso NCBI: NP_005593
• Nº de acceso UniProt: O75508
• Condiciones de envío: wet ice
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... CLDN11(5010)

Descripción

Descripción general

Claudin-11 (CLDN11; or Oligodendrocyte-specific protein) is expressed in Sertoli cells of the testis. It is involved in the formation of tight junctions, which is required for spermatogenesis. Previous studies have indicated that claudin-11 may prevent the progression of bladder cancer by blocking cell invasion and metastatis.

Especificidad

Other homologies: Mouse and Rat (93% sequence homology).

This antibody recognizes the cytoplasmic domain of Claudin-11.

Inmunógeno

Epitope: Cytoplasmic domain

KLH-conjugated linear peptide corresponding to the cytoplasmic domain of human Claudin-11.

Aplicación

Anti-Claudin-11 Antibody is an antibody against Claudin-11 for use in Western Blotting.

Research Category
Cell Structure

Research Sub Category
ECM Proteins

Western Blot Analysis: 1 µg/mL from a representative lot detected Claudin-11 in human kidney tissue lysate.

Western Blot Analysis: 2 µg/mL from a representative lot detected Claudin-11 in human testis tissue lysate.

Calidad

Evaluated by Western Blot in human brain tissue lysate.

Western Blot Analysis: 0.5 µg/mL of this antibody detected Claudin-11 in 10 µg of human brain tissue lysate.

Descripción de destino

~22 kDa observed. An uncharacterized band may be observed at ~60 kDa in some tissue lysates.

Forma física

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Almacenamiento y estabilidad

Stable for 1 year at 2-8°C from date of receipt.

Nota de análisis

Control
Human brain tissue lysate

Otras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable