This product is not sterile.
540223
Purmorphamine
≥98% (HPLC), liquid, Hedgehog signaling activator, Calbiochem
Sinónimos:
InSolution Purmorphamine
Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
Seleccione un Tamaño
5 MG
357,00 €
357,00 €
Póngase en contacto con nuestro Servicio de Atención al Cliente para disponibilidad
Solicitar un pedido a granel
Seleccione un Tamaño
Cambiar Vistas
5 MG
357,00 €
About This Item
Código UNSPSC:
12352116
NACRES:
NA.77
357,00 €
Póngase en contacto con nuestro Servicio de Atención al Cliente para disponibilidad
Solicitar un pedido a granel
Productos recomendados
Nombre del producto
Purmorphamine, InSolution, ≥98%, 50 mM in DMSO, induces osteoblast differentiation in C3H10T1/2 multipotent mesenchymal progenitor cells
Nivel de calidad
Ensayo
≥98% (HPLC)
Formulario
liquid
fabricante / nombre comercial
Calbiochem®
condiciones de almacenamiento
OK to freeze
desiccated (hygroscopic)
protect from light
temp. de almacenamiento
−20°C
Descripción general
A cell-permeable purine compound that induces osteoblast differentiation in C3H10T1/2 multipotent mesenchymal progenitor cells (EC50 = 1 µM) and in MC3T3-E1 lineage-committed preosteoblasts. Also shown to induce transdifferentiation in pre-adipocytes and myoblasts. Its effects are reported to be synergistic with bone morphogenetic protein-4 (BMP-4). Reported to induce osteogenesis by activation of the Hedgehog signaling pathway.
Purmorphamine is a cell-permeable purine compound that induces osteoblast differentiation in C3H10T1/2 multipotent mesenchymal progenitor cells.
Aplicación
InSolution Purmorphamine, CAS 483367-10-8, is a provided as a 50 mM solution in DMSO. Induces osteoblast differentiation of multipotent mesenchymal progenitor cells C3H10T1/2 & lineage-committed preosteoblasts MC3T3-E1.
Envase
Packaged under inert gas
Advertencia
Toxicity: Irritant (B)
Forma física
A 50 mM (5 mg/192 µl) solution of Purmorphamine (Cat. No. 540220) in DMSO.
Reconstitución
Following initial thaw, aliquot and freeze (-20°C).
Otras notas
Wu, X., et al. 2004. Chem. Biol.11, 1229.
Wu, X., et al. 2002. J. Am. Chem. Soc.124, 14520.
Wu, X., et al. 2002. J. Am. Chem. Soc.124, 14520.
Información legal
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Palabra de señalización
Warning
Frases de peligro
Consejos de prudencia
Clasificaciones de peligro
Muta. 2
Código de clase de almacenamiento
10 - Combustible liquids
Clase de riesgo para el agua (WGK)
WGK 2
Punto de inflamabilidad (°F)
188.6 °F - closed cup
Punto de inflamabilidad (°C)
87 °C - closed cup
Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
¿Ya tiene este producto?
Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.
Megumi Kitami et al.
Biochemical and biophysical research communications, 509(1), 222-226 (2018-12-28)
Condylar cartilage is a joint cartilage essential for smooth jaw movement. The importance of ciliary proteins in condylar cartilage development has been reported. However, little is known about how ciliary proteins control the homeostasis of condylar cartilage. Here we show
Arens Taga et al.
Journal of visualized experiments : JoVE, (174) (2021-09-14)
Human pluripotent stem cell-derived astrocytes (hiPSC-A) and neurons (hiPSC-N) provide a powerful tool for modeling Amyotrophic Lateral Sclerosis (ALS) pathophysiology in vitro. Multi-electrode array (MEA) recordings are a means to record electrical field potentials from large populations of neurons and
Aurelie de Rus Jacquet et al.
eLife, 10 (2021-10-01)
Astrocytes are essential cells of the central nervous system, characterized by dynamic relationships with neurons that range from functional metabolic interactions and regulation of neuronal firing activities, to the release of neurotrophic and neuroprotective factors. In Parkinson's disease (PD), dopaminergic
Inge Kinnart et al.
NPJ Parkinson's disease, 10(1), 80-80 (2024-04-10)
The pathogenic effect of SNCA gene multiplications indicates that elevation of wild-type α-synuclein levels is sufficient to cause Parkinson's disease (PD). Mitochondria have been proposed to be a major target of α-synuclein-induced damage. PINK1/parkin/DJ-1-mediated mitophagy is a defense strategy that
Jennifer Pardieck et al.
Stem cell research & therapy, 13(1), 131-131 (2022-03-30)
Spinal interneurons (INs) relay sensory and motor control information between the brain and body. When this relay circuitry is disrupted from injury or disease, it is devastating to patients due to the lack of native recovery in central nervous system
-
Is this product sterlie?
1 respuesta-
¿Le ha resultado útil?
-
Filtros activos
Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.
Póngase en contacto con el Servicio técnico
