5.05873

(R)-Baclofen

• Sinónimos: (R)-Baclofen, STX 209, GABA _B Agonist, Baclofen, Arbaclofen, STX 209, GABA_B Agonist, Baclofen, Arbaclofen
• Fórmula empírica (notación de Hill): C₁₀H₁₂ClNO₂
• Número de CAS: 69308-37-8
• Peso molecular: 213.66
• Código UNSPSC: 12352200

Propiedades

• Análisis: ≥98% (HPLC)
• Nivel de calidad: 100
• formulario: solid
• fabricante / nombre comercial: Calbiochem^®
• condiciones de almacenamiento: OK to freeze; protect from light
• color: off-white
• solubilidad: water: soluble
• temp. de almacenamiento: 2-8°C
• InChI: 1S/C10H12ClNO2/c11-9-3-1-7(2-4-9)8(6-12)5-10(13)14/h1-4,8H,5-6,12H2,(H,13,14)
• Clave InChI: KPYSYYIEGFHWSV-UHFFFAOYSA-N

Descripción

Descripción general

A selective agonist of GABA_B receptors that is shown to activate K+ conductance in hippocampal neurons. Also acts as an antispastic agent and a skeletal muscle relaxant. It is also an experimental drug to treat autism.

Acciones bioquímicas o fisiológicas

Primary Target
GABA_B

Advertencia

Toxicity: Toxic (F)

Reconstitución

Following reconstitution, aliquot and freeze (-20°C. Stock solutions are stable for up to 3 months at -20°C.

Otras notas

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Sodickson, D.L., et al., 1996. J. Neurosci.16, 6374.

Ahuja, S. et al., 1985. Analytical Profile of Drug Substances14, 527.

Información legal

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Pictogramas: GHS06
• Palabra de señalización: Danger
• Frases de peligro: H301
• Consejos de prudencia: P264 - P270 - P301 + P310 - P405 - P501
• Clasificaciones de peligro: Acute Tox. 3 Oral
• Código de clase de almacenamiento: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable