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407125

Sigma-Aldrich

D-myo-Inositol 1,2,3,4,5,6-Hexakisphosphate, Dodecasodium Salt, Zea mays

Major phosphorus compound in plants that chelates with a variety of di- and trivalent cations.

Sinónimos:

D-myo-Inositol 1,2,3,4,5,6-Hexakisphosphate, Dodecasodium Salt, Zea mays, D-Ins(1,2,3,4,5,6)P₆, 12Na, Phytic Acid, 12Na

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About This Item

Fórmula empírica (notación de Hill):
C6H6O24P6 · 12Na
Número de CAS:
14306-25-3
Peso molecular:
923.82
Código UNSPSC:
12352211
NACRES:
NA.77

Nivel de calidad

100

Análisis

≥85% (HPLC)

formulario

solid

fabricante / nombre comercial

Calbiochem®

condiciones de almacenamiento

OK to freeze
desiccated (hygroscopic)

color

white to off-white

solubilidad

water: 1 mg/mL

Condiciones de envío

ambient

temp. de almacenamiento

−20°C

InChI

1S/C6H18O24P6.12Na/c7-31(8,9)25-1-2(26-32(10,11)12)4(28-34(16,17)18)6(30-36(22,23)24)5(29-35(19,20)21)3(1)27-33(13,14)15;;;;;;;;;;;;/h1-6H,(H2,7,8,9)(H2,10,11,12)(H2,13,14,15)(H2,16,17,18)(H2,19,20,21)(H2,22,23,24);;;;;;;;;;;;/q;12*+1/p-12

Clave InChI

KETSPIPODMGOEJ-UHFFFAOYSA-B

Categorías relacionadas

Descripción general

Major phosphorus compound in plants that chelates with a variety of di- and trivalent cations. Reported to suppress damaging iron-catalyzed redox reactions.
Major phosphorus compound in plants. Chelates with a variety of di- and trivalent cations. Inhibits growth and induces differentiation of PC-3 human prostate cancer cells. Also reported to suppress damaging iron-catalyzed redox reactions.

Acciones bioquímicas o fisiológicas

Cell permeable: no
Primary Target
Chelates with a variety of di- and trivalent cations
Product does not compete with ATP.
Reversible: no

Advertencia

Toxicity: Standard Handling (A)

Reconstitución

Following recosntitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Otras notas

Shamsuddin, A.M., and Yang, G.Y. 1995. Carcinogenesis 16, 1975.
Graf, E., and Eaton, J.W. 1993. Nutr. Cancer19, 11.

Información legal

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Hayley Whitfield et al.
The Biochemical journal, 477(14), 2621-2638 (2020-07-25)
Inositol polyphosphates are ubiquitous molecular signals in metazoans, as are their pyrophosphorylated derivatives that bear a so-called 'high-energy' phosphoanhydride bond. A structural rationale is provided for the ability of Arabidopsis inositol tris/tetrakisphosphate kinase 1 to discriminate between symmetric and enantiomeric
Jone Paesmans et al.
eLife, 9 (2020-12-23)
Synaptojanin1 (Synj1) is a phosphoinositide phosphatase, important in clathrin uncoating during endocytosis of presynaptic vesicles. It was identified as a potential drug target for Alzheimer's disease, Down syndrome, and TBC1D24-associated epilepsy, while also loss-of-function mutations in Synj1 are associated with
Yann Desfougères et al.
Methods in molecular biology (Clifton, N.J.), 2091, 59-71 (2019-11-28)
The yeast Saccharomyces cerevisiae has given us much information on the metabolism and function of inositol polyphosphates and inorganic polyphosphate. To expand our knowledge of the metabolic as well as functional connections between inositol polyphosphates and inorganic polyphosphate, we have

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