1.00160

Ácido bórico

crystalline, EMPROVE^® ESSENTIAL, Ph. Eur., BP, JP, NF

• Sinónimos: Orthoboric acid, Trihydroxidoboron
• Fórmula lineal: H₃BO₃
• Número de CAS: 10043-35-3
• Peso molecular: 61.83
• Número MDL: MFCD00011337
• Código UNSPSC: 12352301
• Número índice de la CE: 233-139-2

Propiedades

• Agency: BP; JP; NF; Ph. Eur.
• Nivel de calidad: 500
• presión de vapor: 2.6 mmHg ( 20 °C)
• Línea del producto: EMPROVE^® ESSENTIAL
• Ensayo: 99.5-100.5% dry basis (alkalimetric)
• Formulario: crystalline; solid
• técnicas: API processing | cocrystal formation: suitable; API processing | salt formation: suitable
• pH: 3.8-4.8 (20 °C, 33 g/L in H₂O)
• mp: 160 °C (dec.) (lit.)
• solubilidad: 49.2 g/L
• densidad: 1.489 g/cm³ at 23 °C
• trazas de anión: sulfate (SO₄^2-): ≤0.04%
• trazas de catión: As: ≤0.0001%; heavy metals (as Pb): ≤0.0015%
• aplicaciones: liquid formulation; ophthalmics; pharmaceutical; semi-solid formulation
• temp. de almacenamiento: 2-30°C
• cadena SMILES: OB(O)O
• InChI: 1S/BH3O3/c2-1(3)4/h2-4H
• Clave InChI: KGBXLFKZBHKPEV-UHFFFAOYSA-N

Descripción

Descripción general

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Aplicación

Boric acid has antimicrobial characteristics and is therefore typically used as preservative in pharmaceutical formulations and cosmetics. It is also used as buffering agent and pH adjuster.

Información legal

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Pictogramas: GHS08
• Palabra de señalización: Danger
• Frases de peligro: H360FD
• Consejos de prudencia: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Clasificaciones de peligro: Repr. 1B
• Código de clase de almacenamiento: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable