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LM1701

Avanti

17:1 Lyso PA

Avanti Research™ - A Croda Brand

Sinónimos:

1-(10Z-heptadecenoyl)-sn-glycero-3-phosphate (ammonium salt)

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About This Item

Fórmula empírica (notación de Hill):
C20H42NO7P
Número de CAS:
1246298-35-0
Peso molecular:
439.52
Código UNSPSC:
51191904
NACRES:
NA.25

formulario

methanol solution

envase

pkg of 1 × 1 mL (LM1701-1EA)

fabricante / nombre comercial

Avanti Research™ - A Croda Brand

concentración

~10 μg/mL (Refer to C of A for lot specific concentration. )

aplicaciones

lipidomics
metabolomics

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

cadena SMILES

O[C@](COP([O-])(O)=O)([H])COC(CCCCCCCC/C=C\CCCCCC)=O.[NH4+]

Descripción general

Lysophosphatidic acid (Lyso PA) is a water-soluble lipid, localized to all cells and tissues in mammals.

Aplicación

17:1 Lyso PA or 1-(10Z-heptadecenoyl)-sn-glycero-3-phosphate (ammonium salt) has been used as an internal standard for unsaturated lysophosphatidic acid (LPA) ester and cyclic LPA ethers in reversed-phase ultra-performance liquid chromatography-tandem mass spectrometry (UPLC/MS/MS).

Acciones bioquímicas o fisiológicas

Lysophosphatidic acid (Lyso PA) is considered as a biological modulator of various functions in the cell. It is a potent signaling molecule with growth-factor-like actions. Lyso PA regulates cell proliferation, survival, cytoskeletal modification and calcium influx. It is associated with smooth-muscle contraction and platelet aggregation. It is also known to regulate blood pressure. Lyso PA possess extensive biological actions and is involved in the progression of several human cancer.

Envase

2 mL Amber Glass Sealed Ampule (LM1701-1EA)

Información legal

Avanti Research is a trademark of Avanti Polar Lipids, LLC

también adquirido normalmente con este producto

Referencia del producto
Descripción
Precios

Palabra de señalización

Danger

Clasificaciones de peligro

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Órganos de actuación

Eyes

Código de clase de almacenamiento

3 - Flammable liquids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

49.5 °F - closed cup

Punto de inflamabilidad (°C)

9.7 °C - closed cup

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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MGDG

Oleoyl-L-α-lysophosphatidic acid sodium salt ≥98%, solid

Sigma-Aldrich

L7260

Oleoyl-L-α-lysophosphatidic acid sodium salt

Gordon B Mills et al.
Nature reviews. Cancer, 3(8), 582-591 (2003-08-02)
The bioactive phospholipid lysophosphatidic acid (LPA) stimulates cell proliferation, migration and survival by acting on its cognate G-protein-coupled receptors. Aberrant LPA production, receptor expression and signalling probably contribute to cancer initiation, progression and metastasis. The recent identification of ecto-enzymes that
Mu-En Lin et al.
Prostaglandins & other lipid mediators, 91(3-4), 130-138 (2010-03-25)
Lysophosphatidic acid (LPA), a water-soluble phospholipid, has gained significant attention in recent years since the discovery that it acts as a potent signaling molecule with wide-ranging effects on many different target tissues. There are currently five identified G protein-coupled receptors
T Sasagawa et al.
Journal of nutritional science and vitaminology, 44(6), 809-818 (1999-04-10)
Abnormal phospholipid metabolism may play an important role in the progression of atherosclerosis in renal failure. We analyzed plasma phospholipid and lysophospholipid contents and fatty acid composition in the phospholipids of 18 patients with renal failure on hemodialysis (HD) and
Andrew Draganski et al.
The journal of sexual medicine, 15(5), 645-653 (2018-04-28)
Curcumin, a naturally occurring anti-inflammatory compound, has shown promise in pre-clinical studies to treat erectile dysfunction (ED) associated with type-1 diabetes. However, poor bioavailability following oral administration limits its efficacy. The present study evaluated the potential of topical application of

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