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870817P

Avanti

N-palmitoylglycine

Avanti Research™ - A Croda Brand

Sinónimos:

Glycine, N-(1-oxohexadecyl)-

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10 MG
59,40 €

59,40 €

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10 MG
59,40 €

About This Item

Fórmula empírica (notación de Hill):
C18H35NO3
Número de CAS:
2441-41-0
Peso molecular:
313.48
Número MDL:
MFCD00153471
Código UNSPSC:
12352211
NACRES:
NA.25

59,40 €

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Formulario

powder

envase

pkg of 1 × 10 mg (870817P-10mg)

fabricante / nombre comercial

Avanti Research™ - A Croda Brand

tipo de lípido

neutral glycerides
neutral lipids

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

cadena SMILES

O=C(CCCCCCCCCCCCCCC)NCC(O)=O

InChI

1S/C18H35NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-17(20)19-16-18(21)22/h2-16H2,1H3,(H,19,20)(H,21,22)

Clave InChI

KVTFEOAKFFQCCX-UHFFFAOYSA-N

Descripción general

N-palmitoylglycine belongs to the family of acyl amides, which are endogenous lipids with a potential to modulate pain and inflammation. Structurally, N-palmitoylglycine (PalGly) comprises 16-carbon saturated fatty acid attached to glycine through amide linkage. It is a structural analog of phospholipid-derived N-acyl ethanolamine.[1] N-palmitoylglycine, a saturated lipid is endogenously produced at high levels in rat skin and spinal cord.[1][2]

Aplicación

N-palmitoylglycine has been used as an intact polar lipid (IPL) standard for determination of δ 15N values of nitrogen containing headgroups of IPLs using gas chromatography/combustion/isotope-ratio mass spectrometry.[3]

Acciones bioquímicas o fisiológicas

N-palmitoylglycine stimulates calcium influx and nitric oxide (NO) production through calcium-sensitive nitric-oxide synthase in sensory neurons.[1] It acts as a lipid activator of G-protein-coupled receptor GPR132.[4]

Envase

5 mL Amber Glass Screw Cap Vial (870817P-10mg)

Información legal

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Cyrine Ezzili et al.
Bioorganic & medicinal chemistry letters, 20(20), 5959-5968 (2010-09-08)
Key studies leading to the discovery and definition of the role of endogenous fatty acid amide signaling molecules are summarized.
Neta Rimmerman et al.
Molecular pharmacology, 74(1), 213-224 (2008-04-22)
N-arachidonoyl glycine is an endogenous arachidonoyl amide that activates the orphan G protein-coupled receptor (GPCR) GPR18 in a pertussis toxin (PTX)-sensitive manner and produces antinociceptive and antiinflammatory effects. It is produced by direct conjugation of arachidonic acid to glycine and
Elisabeth Svensson et al.
Rapid communications in mass spectrometry : RCM, 29(23), 2263-2271 (2015-11-03)
Compound-specific isotope analysis (CSIA) of nitrogen in amino acids has proven a valuable tool in many fields (e.g. ecology). Several intact polar lipids (IPLs) also contain nitrogen, and their nitrogen isotope ratios have the potential to elucidate food-web interactions or
Shalini Chaturvedi et al.
Prostaglandins & other lipid mediators, 81(3-4), 136-149 (2006-11-07)
Oleamide (cis-9-octadecenamide) is a member of an emerging class of lipid-signaling molecules, the primary fatty acid amides. A growing body of evidence indicates that oleamide mediates fundamental neurochemical processes including sleep, thermoregulation, and nociception. Nevertheless, the mechanism for oleamide biosynthesis
Heather B Bradshaw et al.
Vitamins and hormones, 81, 191-205 (2009-08-04)
Discovery of the endogenous cannabinoid and N-acyl amide, anandamide (N-arachidonoyl ethanolamine), paved the way for lipidomics discoveries in the growing family of N-acyl amides. Lipidomics is a field that is broadening our view of the molecular world to include a
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