Saltar al contenido
Merck
Todas las fotos(2)

Documentos clave

Ver Toda la documentación

850336P

Avanti

MAPCHO™-12

Avanti Research™ - A Croda Brand

Sinónimos:

DPC; Fos-Choline-12; FOS12; FC-12

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización

Seleccione un Tamaño

1 G
330,00 €
5 G
1280,00 €
25 G
4870,00 €

330,00 €

Póngase en contacto con nuestro Servicio de Atención al Cliente para disponibilidad
Solicitar un pedido a granel
Todas las fotos(2)

Seleccione un Tamaño

Cambiar Vistas
1 G
330,00 €
5 G
1280,00 €
25 G
4870,00 €

About This Item

Fórmula empírica (notación de Hill):
C17H38NO4P
Número de CAS:
29557-51-5
Peso molecular:
351.46
Número MDL:
MFCD00674306
Código UNSPSC:
12352211
NACRES:
NA.25

330,00 €

Póngase en contacto con nuestro Servicio de Atención al Cliente para disponibilidad
Solicitar un pedido a granel

descripción

n-dodecylphosphocholine

Ensayo

>99% (TLC)

Formulario

powder

envase

pkg of 1 × 1 g (850336P-1g)
pkg of 1 × 25 g (850336P-25g)
pkg of 1 × 5 g (850336P-5g)

fabricante / nombre comercial

Avanti Research™ - A Croda Brand

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

cadena SMILES

[P](=O)([O-])(OCC[N+](C)(C)C)OCCCCCCCCCCCC

InChI

1S/C17H38NO4P/c1-5-6-7-8-9-10-11-12-13-14-16-21-23(19,20)22-17-15-18(2,3)4/h5-17H2,1-4H3

Clave InChI

QBHFVMDLPTZDOI-UHFFFAOYSA-N

Descripción general

Dodecylphosphocholine is a structural analog of lauroyl lysophosphatidylcholine that is more stable to hydrolytic degradation. The lipid is often used as a detergent for membrane protein solubilization and purification.Dodecylphosphocholine has been shown to improve paracellular permeability of hydrophilic compounds by modulating the tight junctions. This may have implications on its use for oral or nasal drug delivery.
MAPCHO™-12 or n-dodecylphosphocholine is a detergent with short chain.[1]

Aplicación

MAPCHO™-12 is suitable for use as detergent for B. subtilis cytochrome b558 protein for nuclear magnetic resonance experiments.[2] It is also suitable for use in the purification of cytoplasmic tail of gp41 (gp41CT) protein and micelle preparation.[3]

Acciones bioquímicas o fisiológicas

MAPCHO™-12 or n-dodecylphosphocholine in combination with 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is used for membrane-mimetic bicelle system for orientation based studies in membrane proteins.[1] It provides a zwitterionic surface in the membrane micelle structure.[4]

Envase

125 mL Amber Wide Mouth Glass Bottle with Screw Cap (850336P-5g)
20 mL Clear Glass Screw Cap Vial (850336P-1g)
250 mL Amber Wide Mouth Glass Bottle with Screw Cap (850336P-25g)

Información legal

Avanti Research is a trademark of Avanti Polar Lipids, LLC
MAPCHO is a trademark of Avanti Polar Lipids, LLC

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Elija entre una de las versiones más recientes:

Certificados de análisis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documentos section.

Si necesita más asistencia, póngase en contacto con Atención al cliente

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Nina Liu et al.
Heliyon, 5(12), e03018-e03018 (2020-01-01)
Fusion of host and viral membranes is a crucial step during infection by enveloped viruses. In the structurally-defined "class I″ viral glycoproteins, the formation of a highly stable α-helical bundle by the ectodomain of the fusion subunit (e.g., GP2 for
Magnetically oriented dodecylphosphocholine bicelles for solid-state NMR structure analysis
Nolandt OV, et al.
Biochimica et Biophysica Acta - Biomembranes, 1818(5), 1142-1147 (2012)
Solution structure and membrane interaction of the cytoplasmic tail of HIV-1 gp41 protein
Murphy RE, et al.
Structure, 25(11), 1708-1718 (2017)
Pasquale Palladino et al.
Journal of fluorescence, 20(1), 191-196 (2009-09-17)
We have investigated the effect of ionic strength on the aggregation behavior of n-dodecyl phosphocholine. On the basis of the classical Corrin-Harkins relation, the critical micellar concentration of this detergent decreases with a biphasic trend on lithium chloride addition. It
N P Santisteban et al.
Biochimica et biophysica acta. Biomembranes, 1862(5), 183199-183199 (2020-01-29)
The lipid bilayer disrupting effect of antimicrobial peptides (AMPs) has been widely studied in model-lipid systems by applying biophysical techniques such as 2H NMR spectroscopy. Real bacteria cell envelopes contain non-lipid components, such as peptidoglycan, and thus it is important
Ver todos los artículos relacionados

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico